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| Title / Description | Primary chronic lymphocytic leukemia cell response to purine nucleoside analog LMP-420 |
| Accession | GSE20211 |
| Summary | Analysis of chronic lymphocytic leukemia (CLL) patient cells cultured with LMP-420 (2 uM) for 24 hr. LMP-420 is an anti-inflammatory agent that induces CLL cell apoptosis in vitro without impairing normal immune cells. Results provide insight into the mechanism of action of LMP-420 in CLL. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | LMP-420 |
| Smiles | B(CCCCCN1C=NC2=C1N=C(N=C2Cl)N)(O)O |
| Pubchem_cid | 497668 |
| Cell_type | Primary chronic lymphocytic leukemia cell - 2 uM for 24 Hours |
| Organism | human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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