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| Title / Description | Amyloid precursor protein double mutant and amyloid precursor-like protein 2 deficiency effects on adult brain regions |
| Accession | GDS4134 |
| Summary | Analysis of prefrontal cortices and hippocampi from C57BL/6 adults: APLP2-KO (APLP2-/-) or APPsα-DM (APPα/αAPLP2-/-). Amyloid precursor protein (APP) and AP-like protein 2 (APLP2) play key roles in Alzheimer pathogenesis. Results provide mechanistic insights into APP/APLP2-mediated functions. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | True |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 1000 |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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