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| Title / Description | Alzheimer's disease: induced pluripotent stem cells with Presenilin 2 mutation (N141) |
| Accession | GDS4141 |
| Summary | Analysis of 2 iPSC clones with presenilin 2 (PS2) mutation N141, established by retroviral transduction of fibroblasts from a Familial Alzheimer’s disease (FAD) patient. PS2 mutations are causative factors for autosomal-dominant early-onset FAD. Results provide insight into molecular basis of FAD. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | True |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 1000 |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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