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GEN3VA Reports for these tags

DRUGS_BD2K_LINCS_DCIC_COURSERA

SOFT file
Title / Description Expression data from human alternatively activated macrophages
Accession GSE16386
Summary Human CD14 positive monocytes were purified from healthy volunteers’ blood and cultured in vitro for 6 hours. While culturing, macrophages were activated alternatively with interleukin-4 (IL-4 100 ng/ml). Simultaneously, macrophages were also treated with vehicle (DMSO:ethanol) or 1uM synthetic PPARg agonist, Rosiglitazone. We used Affymetrix microarrays (U133Plus 2.0) to analyze activation and PPARg-induced gene expression changes.
Organism Homo sapiens
Platform GPL570
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Cell_type macrophage
Drug_id DB00412
Drug_name Rosiglitazone
Organism Human
Visualizations
Principal Component Analysis
Hierarchical clustering
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA Crowdsourcing
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