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| Title / Description | TGFß1-driven epithelial to mesenchymal transition in human kidney cell line |
| Accession | GSE23338 |
| Summary | TGFbeta is the major cytokine driver of fibrosis in the kidney and other tissue. Epithelial-mesenchymal transition has been postulated to contibrute to renal fibrosis in diseases such as diabetic nephropathy. We wished to identify novel genes that were upregulated in human kidney epithelial cells in response to TGFb1.The transcriptional responses for human proximal tubule epithelial cells to 10 ng/ml TGFbeta1 was examined over 24 and 48 hr |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | human kidney proximal tubule epithelial cell line HK2 |
| Perturbation | TGFβ1 // 24 hours |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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