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| Title / Description | Genome-wide analysis of gene expression in lung cells from metformin treated Mycobacterium tuberculosis infected mice |
| Accession | GSE57275 |
| Summary | Analysis of Metfromin induced changes in the lung cells of Mycobacterium tuberculosis infected mouse at gene expression level. The hypothesis tested in the present study was whether metformin has any effect on the host immune response in Mycobacterium tuberculosis infected mice? Results provide important information on the effect of metformin on the inflammatory response and immune activation associated with mycobacterial infection. In conclusion, Metfromin normalizes the chronic inflammation associated with Mycobacterium tuberculosis infection. |
| Organism | Mus musculus |
| Platform | GPL6887 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Lung |
| Perturbation | Metformin |
| Concentration | 500 mg/Kg |
| Disease | Tuberculosis |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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