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| Title / Description | Atorvastatin treatment of familial combined hyperlipidemia: peripheral blood monocytes |
| Accession | GSE11393 |
| Summary | Analysis of monocytes from male, familial combined hyperlipidemia (FCH) patients following 4 wks of treatment with atorvastatin, an HMG-CoA reductase inhibitor that slows the production of cholesterol. Results provide insight into molecular mechanisms underlying the pathogenesis of FCH. |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Atorvastatin |
| Smiles | OC(CC(CC(=O)[O-])O)CCn1c(C(C)C)c(c(c1c1ccc(cc1)F)c1ccccc1)C(=O)Nc1ccccc1 |
| Drugbank_id | DB01076 |
| Cell_type | Monocytes from (male, familial combined hyperlipidemia (FCH) patients) - following 4 weeks of treatment |
| Organism | human |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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