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GEN3VA Reports for these tags

DRUGS_BD2K_LINCS_DCIC_COURSERA

SOFT file
Title / Description Expression data of cystic fibrosis and non-cystic fibrosis airway cell lines under oxidative stress
Accession GSE39843
Summary CF's physiopathology is poorly explained by the mutation alone. The oxydative stress could be a major factor of this illness . Study its impact on transcriptome's CF cell line could be ameliorate our understanding of the evolution of cystic fibrosis. we used microarray technology to evaluate under oxydative stress, the transcriptional state of an epithelial lung cell issued from a human with cystic fibrosis and to identify a set of modulated genes associated to survival cell processes.
Organism Homo sapiens
Platform GPL570
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Drug_name 2,3-dimethoxy-1,4-naphtoquinone (DMNQ)
Smiles COC1=C(C(=O)C2=CC=CC=C2C1=O)OC
Pubchem_cid 3136
Cell_type epithelial lung cells
Organism human
Visualizations
Principal Component Analysis
Hierarchical clustering
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA Crowdsourcing
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