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| Title / Description | An immediate transcriptional signature predicts response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts |
| Accession | GSE69346 |
| Summary | Gene expression analysis of three sets of patient-derived T-ALL xenografted murine lines treated or not treated with Givinostat, to investigate the immediate anti-leukemic effects after 6 hours of in vivo treatment with this histone deacetylase inhibitor. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell_type | T-ALL cells |
| Drug_id | CID 9804992 |
| Drug_name | Givinostat |
| Organism | Human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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