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| Title / Description | Bone marrow microenvironment effect on imatinib-treated chronic myeloid leukemia CD34+ cells |
| Accession | GDS4756 |
| Summary | Analysis of CML cells treated with tyrosine kinase inhibitor (TKI) imatinib and BM mesenchymal stromal cells (MSCs). Coculture with MSCs protects the CML cells from TKI-mediated cell death and depletion. Results provide insight into microenvironmental protection of CML cells from TKI treatment. |
| Organism | Homo sapiens |
| Platform | GPL6244 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell_type | CD34+ cells |
| Drug_id | DB00619 |
| Drug_name | Imatinib |
| Organism | Human |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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