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| Title / Description | TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ |
| Accession | GDS4071 |
| Summary | Analysis of HMEC-TR cells silenced for TIF1γ or Smad4 and treated with TGFβ. A strong EMT increase was observed in TIF1γ-silenced cells after TGFβ1 treatment; Smad4 inactivation completely blocked this process. Results show the relationship between TIF1γ and Smad4 in TGF-β signaling and EMT. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Ligand_name | TGF-beta |
| Ligand_id | 7040 |
| Cell_type | HMEC-TR mammary epithelial cell line |
| Organism | human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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