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| Title / Description | Rheumatoid arthritic synovium response to rituximab |
| Accession | GDS4903 |
| Summary | Analysis of synovial biopsy samples from anti-TNF resistant rheumatoid arthritis (RA) patients 12 wks after the start of rituximab (RTX) therapy. RTX is a mAb against CD20, expressed on subsets of B cells. Results provide insight into how RTX-induced B cell depletion interferes with RA pathogenesis. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Synovium |
| Perturbation | rituximab |
| Disease | Rheumatoid arthritis |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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| Combined |
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