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| Title / Description | Proteasome inhibitor Bortezomib effect on MCF7 breast cancer cells |
| Accession | GDS4089 |
| Summary | Analysis of MCF7 cells stimulated with bortezomib (velcade). Proteasome inhibition can regulate estrogen-induced transcription. Results provide insight into the mechanisms by which proteasome inhibition influences ERα function and may uncover improved strategies for the treatment of breast cancer. |
| Organism | Homo sapiens |
| Platform | GPL10558 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell_type | Breast |
| Drug_id | DB00188 |
| Drug_name | Bortezomib |
| Organism | Human |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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