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| Title / Description | CD3+ T cell response to stimulation with CD3/CD28 or nitric oxide |
| Accession | GDS4188 |
| Summary | Analysis of healthy T cells stimulated with CD3/CD28 (a Ca2+ fluxing inducer) or NO (a key trigger of mitochondrial hyperpolarization (MHP)). Enhanced Ca2+ fluxing and MHP underlie aberrant T-cell activation in SLE. Results provide insight into the molecular basis of T cell dysfunction in lupus. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell_type | CD3+ T cell |
| Drug_id | CID 145068 |
| Drug_name | Nitric oxide |
| Organism | Human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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