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GEN3VA Reports for these tags

PATHOGENS_BD2K_LINCS_DCIC_COURSERA

SOFT file
Title / Description Expression data of A2EN cells during early stage of Chlamydia trachomatis infection
Accession GSE54336
Summary Chlamydia trachomatis is an obligate intracellular pathogen that causes trachoma and sextually transmitted disease in human. During early stage of infection, Chlamydia secreted bacterial effector proteins into host cell cytoplasm to help its entry and estabilishment of early replicated niche. We identified a Chlamydia mutant that lack an early Effector. To address the function of this effector, we infected A2EN cells with this mutant (G1V) and its complemented counterpart (G1TEPP) to see what host gene transcriptions are affected by this effector.
Organism Homo sapiens
Platform GPL571
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Microbe_id 813
Microbe_name Chlamydia trachomatis
Cell_type A2EN (Human endocervical epithelial) cells
Organism human
Visualizations
Principal Component Analysis
Hierarchical clustering
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA Crowdsourcing
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