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| Title / Description | Long-term pioglitazone effect on triple transgenic model of Alzheimer's disease (3xTg-AD): hippocampus |
| Accession | GDS4413 |
| Summary | Analysis of hippocampus from 10 month-old, triple-transgenic AD females treated with the thiazolidinedione pioglitazone (PIO) for 14 weeks. TZDs exert cognitive benefits early in the AD process. Results provide insight into molecular mechanisms underlying the neuroprotective role of PIO in AD. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | True |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 1000 |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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