Other Tissues (40), custom report for AGING_M

All reports

Gene signatures

Signatures (40) and Custom Report Builder
Title Organism Platform
1 Age effect on skeletal muscle precursor cells Mus musculus Mus musculus
2 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
3 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
4 Desmin deficiency effect on young and adult skeletal muscles Mus musculus Mus musculus
5 Aging effect on bone marrow hematopoietic stem cells Homo sapiens Homo sapiens
6 Williams-Beuren Syndrome: fibroblast cell lines Homo sapiens Homo sapiens
7 Young and aged skeletal muscles response to long-term vigorous endurance exercise Homo sapiens Homo sapiens
8 Vitamin E supplementation effect on aged heart Mus musculus Mus musculus
9 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
10 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
11 Age effect on hematopoietic stem cells Mus musculus Mus musculus
12 Muscle function and aging - female (HG-U133B) Homo sapiens Homo sapiens
13 Cardiac aging Rattus norvegicus Rattus norvegicus
14 Muscle function and aging - male (HG-U133B) Homo sapiens Homo sapiens
15 Expression data from whole lateral ventricle choroid plexus tissue of young (two months old) and aged (eighteen months old) CD1 male mice. Mus musculus Mus musculus
16 Altered lipid metabolism in the aging kidney identified by three layered omic analysis Mus musculus Mus musculus
17 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
18 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
19 Mitochondrial gene expression decline in aging is tissue-specific and independent of mitochondrial number Mus musculus Mus musculus
20 Microarray analysis of gene expression in aging in mouse sabmandibular gland. Mus musculus Mus musculus
21 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
22 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
23 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
24 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 5) Homo sapiens Homo sapiens
25 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
26 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
27 P38 signaling underlies a cell-autonomous loss of stem cell self-renewal in aged muscle Mus musculus Mus musculus
28 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
29 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
30 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
31 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
32 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
33 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
34 Age effect on myoblast progenitors Mus musculus Mus musculus
35 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
36 Aging lungs and genetic background Mus musculus Mus musculus
37 Aging lungs and genetic background Mus musculus Mus musculus
38 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
39 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
40 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus

PCA

Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.

Genes

Hierarchical clustering of genes based on weights from the differential expression method.

Enrichr

Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.

Hierarchical clustering of enriched terms from

L1000CDS2

L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.