Report01-IFNgamma, custom report for IFNGAMMA

All reports

Gene signatures

Signatures (28) and Custom Report Builder
Title Organism Platform
1 Interferon-gamma effect on lipopolysaccharide-activated bone marrow-derived macrophages Mus musculus Mus musculus
2 Comparison of bone marrow-derived macrophages from BALB/c and C57BL/6 mice with and without interferon-gamma stimulation. Mus musculus Mus musculus
3 Comparison of bone marrow-derived macrophages from BALB/c and C57BL/6 mice with and without interferon-gamma stimulation. Mus musculus Mus musculus
4 Gene expression profile of human epidermal keratinocytes in response to IFNgamma, IL-4, IL-6, IL-17A and IL-22 Homo sapiens Homo sapiens
5 Contribution of the STAT1alpha and STAT1beta isoforms to IFN-gamma mediated innate immunity Mus musculus Mus musculus
6 Bone marrow macrophage (BMMF) response to IFNgR+FcgRI coincidence detection Mus musculus Mus musculus
7 Contribution of the STAT1alpha and STAT1beta isoforms to IFN-gamma mediated innate immunity Mus musculus Mus musculus
8 TPL-2;ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I interferon production Mus musculus Mus musculus
9 TPL-2;ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I interferon production Mus musculus Mus musculus
10 Defining precision probes which differentiate between the activity of type I and type II interferons. Homo sapiens Homo sapiens
11 Distinct roles for IL-27 and IFN-g in the development of T-bet+ Treg required to limit infection-induced pathology Mus musculus Mus musculus
12 Defining precision probes which differentiate between the activity of type I and type II interferons. Homo sapiens Homo sapiens
13 Distinct roles for IL-27 and IFN-g in the development of T-bet+ Treg required to limit infection-induced pathology Mus musculus Mus musculus
14 Defining precision probes which differentiate between the activity of type I and type II interferons. Homo sapiens Homo sapiens
15 Defining precision probes which differentiate between the activity of type I and type II interferons. Homo sapiens Homo sapiens
16 Expression profiling in Wild-type and C-JUN knockout MEFs treated with IFNgamma and cycloheximide Mus musculus Mus musculus
17 Gene expression profiling of primary human hepatocytes treated with IFN-alpha or IFN-gamma Homo sapiens Homo sapiens
18 IFN-gamma activation of cultured neonatal rat microglia Rattus norvegicus Rattus norvegicus
19 TPL-2;ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I interferon production [Set 2] Mus musculus Mus musculus
20 TPL-2;ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I interferon production [Set 2] Mus musculus Mus musculus
21 Gene expression profiling of primary human hepatocytes treated with IFN-alpha or IFN-gamma Homo sapiens Homo sapiens
22 TCL001: Calu-3 cells treated with either IFN alpha or gamma Homo sapiens Homo sapiens
23 TCL001: Calu-3 cells treated with either IFN alpha or gamma Homo sapiens Homo sapiens
24 TCL001: Calu-3 cells treated with either IFN alpha or gamma Homo sapiens Homo sapiens
25 Gene expression analysis of macrophages from ankylosing spondylitis patients reveals interferon-gamma dysregulation Homo sapiens Homo sapiens
26 STAT1 independent control of a neurotropic measles virus challenge in primary neurons and infected mice Mus musculus Mus musculus
27 STAT1 independent control of a neurotropic measles virus challenge in primary neurons and infected mice Mus musculus Mus musculus
28 STAT1 independent control of a neurotropic measles virus challenge in primary neurons and infected mice Mus musculus Mus musculus

PCA

Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.

Genes

Hierarchical clustering of genes based on weights from the differential expression method.

Enrichr

Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.

Hierarchical clustering of enriched terms from

L1000CDS2

L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.