| Title | Organism | Platform | |
|---|---|---|---|
| 1 | Caloric restriction effect on the aged heart and adipose tissue | Rattus norvegicus | Rattus norvegicus |
| 2 | Caloric restriction effect on the aged heart and adipose tissue | Rattus norvegicus | Rattus norvegicus |
| 3 | Streptozotocin-induced diabetic model with acute myocardial infarction: time course | Rattus norvegicus | Rattus norvegicus |
| 4 | Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle | Mus musculus | Mus musculus |
| 5 | Expression data from whole lateral ventricle choroid plexus tissue of young (two months old) and aged (eighteen months old) CD1 male mice. | Mus musculus | Mus musculus |
| 6 | Cardiac aging | Rattus norvegicus | Rattus norvegicus |
| 7 | Vitamin E supplementation effect on aged heart | Mus musculus | Mus musculus |
| 8 | Coenzyme Q10-dependent gene expression in SAMP1 mice tissues | Mus musculus | Mus musculus |
| 9 | Rapamycin extends life span, but has limited effects on aging in mice | Mus musculus | Mus musculus |
Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.
Hierarchical clustering of genes based on weights from the differential expression method.
Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.
Hierarchical clustering of enriched terms from
L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.
