| Title | Organism | Platform | |
|---|---|---|---|
| 1 | Transcription factor Yin Yang 1 deficiency effect on the skeletal muscle | Mus musculus | Mus musculus |
| 2 | Transcription factors YY2 and YY1 knockdown effect on HeLa cells | Homo sapiens | Homo sapiens |
| 3 | Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity | Mus musculus | Mus musculus |
| 4 | Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity | Mus musculus | Mus musculus |
| 5 | Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity | Mus musculus | Mus musculus |
| 6 | Expression profiling in control and YY1 knockout mouse intestinal crypt epithelia | Mus musculus | Mus musculus |
| 7 | Expression changes in Yy1 knock down mouse embryonic stem cells | Mus musculus | Mus musculus |
Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.
Hierarchical clustering of genes based on weights from the differential expression method.
Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.
Hierarchical clustering of enriched terms from
L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.