ABCC6P2 Gene

Name ATP-binding cassette, sub-family C, member 6 pseudogene 2
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe study detailed in one of the provided abstracts (PMID:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "explores a novel mechanism of hair follicle lumen formation. It documents how keratinocytes expressing keratin 79 (K79) migrate outward from developing hair buds during embryogenesis—the same migratory process that is later recapitulated during adult hair regeneration—to form a central hair canal. These migratory K79(+) cells contribute to establishing a distinct, multilayered infundibulum maintained by Lrig1(+) stem cell progeny, thereby reinforcing proper hair follicle architecture.\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nDespite the depth of insight into the cellular mechanics of epithelial tube and hair canal formation, the abstract does not mention or provide any data pertaining to the function of ABCC6P2. Consequently, there is currently no reported evidence or characterization of ABCC6P2 within these findings. Further investigations would be required to elucidate any biological role or mechanistic involvement of ABCC6P2 in these processes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Natalia A Veniaminova, Alicia N Vagnozzi, Daniel Kopinke, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.101725"}], "href": "https://doi.org/10.1242/dev.101725"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24198274"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24198274"}]}]}]}
NCBI Gene ID 730013
API
Download Associations
Predicted Functions View ABCC6P2's ARCHS4 Predicted Functions.
Co-expressed Genes View ABCC6P2's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View ABCC6P2's ARCHS4 Predicted Functions.

Functional Associations

ABCC6P2 has 805 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 16 datasets.

Click the + buttons to view associations for ABCC6P2 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of ABCC6P2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of ABCC6P2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at ABCC6P2 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of ABCC6P2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of ABCC6P2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing ABCC6P2 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of ABCC6P2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of ABCC6P2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of ABCC6P2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of ABCC6P2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of ABCC6P2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of ABCC6P2 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of ABCC6P2 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations gene perturbations changing expression of ABCC6P2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at ABCC6P2 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of ABCC6P2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.