HGNC Family | G protein-coupled receptors |
Name | adhesion G protein-coupled receptor E4, pseudogene |
Description | This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008] |
Synonyms | EMR4P, EMR4, GPR127, PGR16, FIRE |
Proteins | EMR4_HUMAN |
NCBI Gene ID | 326342 |
API | |
Download Associations | |
Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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ADGRE4P has 1,101 functional associations with biological entities spanning 7 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 31 datasets.
Click the + buttons to view associations for ADGRE4P from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of ADGRE4P gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of ADGRE4P gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of ADGRE4P gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
CellMarker Gene-Cell Type Associations | cell types associated with ADGRE4P gene from the CellMarker Gene-Cell Type Associations dataset. | |
ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of ADGRE4P gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
ChEA Transcription Factor Targets | transcription factors binding the promoter of ADGRE4P gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing ADGRE4P protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of ADGRE4P gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
COSMIC Cell Line Gene Mutation Profiles | cell lines with ADGRE4P gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at ADGRE4P gene from the ENCODE Histone Modification Site Profiles dataset. | |
ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of ADGRE4P gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
ENCODE Transcription Factor Targets | transcription factors binding the promoter of ADGRE4P gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing ADGRE4P from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with ADGRE4P gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing ADGRE4P from the GeneSigDB Published Gene Signatures dataset. | |
GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of ADGRE4P gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of ADGRE4P gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of ADGRE4P gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of ADGRE4P gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of ADGRE4P gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
GO Biological Process Annotations 2023 | biological processes involving ADGRE4P gene from the curated GO Biological Process Annotations 2023 dataset. | |
GO Molecular Function Annotations 2023 | molecular functions performed by ADGRE4P gene from the curated GO Molecular Function Annotations 2023 dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of ADGRE4P gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of ADGRE4P gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
GWASdb SNP-Disease Associations | diseases associated with ADGRE4P gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
GWASdb SNP-Phenotype Associations | phenotypes associated with ADGRE4P gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of ADGRE4P gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of ADGRE4P gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain ADGRE4P protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of ADGRE4P gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of ADGRE4P gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |