ALDH3A2 Gene

HGNC Family	Aldehyde dehydrogenases (ALDH)
Name	aldehyde dehydrogenase 3 family, member A2
Description	Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n ALDH3A2, also known as fatty aldehyde dehydrogenase (FALDH), plays a critical role in oxidizing long‐chain fatty aldehydes to their corresponding fatty acids, thereby detoxifying reactive lipid species that arise from processes such as lipid peroxidation, sphingolipid metabolism, and even phytol degradation. This enzymatic activity is essential for protecting cellular membranes, peroxisomes, and other organelles from oxidative damage. In adipocytes and keratinocytes, ALDH3A2 helps maintain cellular redox balance and proper lipid homeostasis, contributing to insulin action and preventing the accumulation of toxic aldehydes that might otherwise trigger oxidative stress responses."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Distinct alternatively spliced variants of ALDH3A2 show different subcellular localizations—some targeting the endoplasmic reticulum while others associate with peroxisomal membranes—ensuring that detoxification functions are deployed in an organelle‐specific manner. Structural studies have further revealed a “gatekeeper” helix that regulates substrate access and enforces specificity for long‐chain aldehydes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " In addition, ALDH3A2 is transcriptionally regulated by factors such as PPARα, reinforcing its role in lipid metabolism and energy homeostasis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Deficiencies or mutations in ALDH3A2 cause Sjögren–Larsson syndrome (SLS), a neurocutaneous disorder characterized by ichthyosis, spasticity, and intellectual disability. In SLS, loss-of-function mutations result in a toxic accumulation of fatty aldehydes that disrupt normal skin and neural development."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "8"}]}, {"type": "t", "text": " Moreover, studies have demonstrated that ALDH3A2 contributes to the metabolism of sphingosine 1-phosphate degradation products and phytol, underlining its broader importance in lipid-derived signaling and detoxification pathways."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Recent investigations have also implicated ALDH3A2 in maintaining mitochondrial and cellular integrity by mitigating oxidative stress in various cell types, including adipocytes where its activity supports insulin signaling and protects against reactive oxygen species."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Additionally, targeted studies in hematopoietic and other malignant cells suggest that disruption of ALDH3A2 function may render such cells more vulnerable to oxidative damage."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": " Collectively, these findings position ALDH3A2 as a pivotal enzyme in lipid aldehyde metabolism, with its dysfunction closely linked to metabolic and neurocutaneous disorders, making it a promising target for therapeutic intervention."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "16"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Damien Demozay, Stéphane Rocchi, Jean-Christophe Mas, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M312062200"}], "href": "https://doi.org/10.1074/jbc.M312062200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14638678"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14638678"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Rebeca González-Fernández, Jairo Hernández, Pablo Martín-Vasallo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression Levels of the Oxidative Stress Response Gene ALDH3A2 in Granulosa-Lutein Cells Are Related to Female Age and Infertility Diagnosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Reprod Sci (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1933719115607996"}], "href": "https://doi.org/10.1177/1933719115607996"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26449735"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26449735"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Markus A Keller, Ulrich Zander, Julian E Fuchs, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms5439"}], "href": "https://doi.org/10.1038/ncomms5439"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25047030"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25047030"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Linda M Sanderson, Tatjana Degenhardt, Arjen Koppen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00370-09"}], "href": "https://doi.org/10.1128/MCB.00370-09"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19805517"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19805517"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "William B Rizzo "}, {"type": "b", "children": [{"type": "t", "text": "Sjögren-Larsson syndrome: molecular genetics and biochemical pathogenesis of fatty aldehyde dehydrogenase deficiency."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Genet Metab (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ymgme.2006.08.006"}], "href": "https://doi.org/10.1016/j.ymgme.2006.08.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16996289"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16996289"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Gael Carney, Shu Wei, William B Rizzo "}, {"type": "b", "children": [{"type": "t", "text": "Sjögren-Larsson syndrome: seven novel mutations in the fatty aldehyde dehydrogenase gene ALDH3A2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.9262"}], "href": "https://doi.org/10.1002/humu.9262"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15241804"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15241804"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Holly Engelstad, Gael Carney, Dana S'aulis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Large contiguous gene deletions in Sjögren-Larsson syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Genet Metab (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ymgme.2011.05.015"}], "href": "https://doi.org/10.1016/j.ymgme.2011.05.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21684788"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21684788"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "S Udhaya Kumar, D Thirumal Kumar, Pinky D Mandal, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Adv Protein Chem Struct Biol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/bs.apcsb.2019.11.004"}], "href": "https://doi.org/10.1016/bs.apcsb.2019.11.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32085885"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32085885"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Kanae Nakahara, Aya Ohkuni, Takuya Kitamura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2012.04.033"}], "href": "https://doi.org/10.1016/j.molcel.2012.04.033"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22633490"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22633490"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Daan M van den Brink, Joram N I van Miert, Georges Dacremont, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of fatty aldehyde dehydrogenase in the breakdown of phytol to phytanic acid."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Genet Metab (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ymgme.2004.01.019"}], "href": "https://doi.org/10.1016/j.ymgme.2004.01.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15110319"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15110319"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Rushdia Zareen Yusuf, Borja Saez, Azeem Sharda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood.2019001808"}], "href": "https://doi.org/10.1182/blood.2019001808"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32458004"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32458004"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Bunichiro Ashibe, Toshitake Hirai, Kyoichiro Higashi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase are achieved by alternative splicing."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M611853200"}], "href": "https://doi.org/10.1074/jbc.M611853200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17510064"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17510064"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "William B Rizzo, Debra A Craft, Tara Somer, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "The combination of whole-exome sequencing and clinical analysis allows better diagnosis of rare syndromic retinal dystrophies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Ophthalmol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/aos.14095"}], "href": "https://doi.org/10.1111/aos.14095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30925032"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30925032"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Maximilian Weustenfeld, Reiner Eidelpes, Matthias Schmuth, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genotype and phenotype variability in Sjögren-Larsson syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.23679"}], "href": "https://doi.org/10.1002/humu.23679"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30372562"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30372562"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Subhashis Banerjee, Sarbani Ghoshal, Todd D Porter "}, {"type": "b", "children": [{"type": "t", "text": "Activation of AMP-kinase by policosanol requires peroxisomal metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Lipids (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s11745-011-3540-6"}], "href": "https://doi.org/10.1007/s11745-011-3540-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21359855"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21359855"}]}]}]}
Synonyms	SLS, ALDH10
Proteins	AL3A2_HUMAN
NCBI Gene ID	224
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

ALDH3A2 has 9,854 functional associations with biological entities spanning 9 categories (molecular profile, organism, disease, phenotype or trait, chemical, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 122 datasets.

Click the + buttons to view associations for ALDH3A2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

ALDH3A2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ALDH3A2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of ALDH3A2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of ALDH3A2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of ALDH3A2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ALDH3A2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of ALDH3A2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ALDH3A2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ALDH3A2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of ALDH3A2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of ALDH3A2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with ALDH3A2 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with ALDH3A2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ALDH3A2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of ALDH3A2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of ALDH3A2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with ALDH3A2 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of ALDH3A2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing ALDH3A2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing ALDH3A2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with ALDH3A2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with ALDH3A2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of ALDH3A2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with ALDH3A2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with ALDH3A2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with ALDH3A2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of ALDH3A2 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by ALDH3A2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving ALDH3A2 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving ALDH3A2 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with ALDH3A2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with ALDH3A2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with ALDH3A2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with ALDH3A2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for ALDH3A2 protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ALDH3A2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ALDH3A2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of ALDH3A2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing ALDH3A2 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with ALDH3A2 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with ALDH3A2 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.