ARHGEF35 Gene

HGNC Family	Rho guanine nucleotide exchange factors (ARHGEF)
Name	Rho guanine nucleotide exchange factor (GEF) 35
Synonyms	ARHGEF5L
Proteins	ARG35_HUMAN
NCBI Gene ID	445328
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

ARHGEF35 has 1,339 functional associations with biological entities spanning 6 categories (molecular profile, organism, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 30 datasets.

Click the + buttons to view associations for ARHGEF35 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

ARHGEF35 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ARHGEF35 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of ARHGEF35 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ARHGEF35 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of ARHGEF35 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ARHGEF35 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of ARHGEF35 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of ARHGEF35 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with ARHGEF35 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ARHGEF35 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ARHGEF35 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of ARHGEF35 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing ARHGEF35 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of ARHGEF35 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of ARHGEF35 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of ARHGEF35 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of ARHGEF35 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of ARHGEF35 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of ARHGEF35 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of ARHGEF35 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of ARHGEF35 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of ARHGEF35 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for ARHGEF35 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of ARHGEF35 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of ARHGEF35 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for ARHGEF35 from the Pathway Commons Protein-Protein Interactions dataset.
	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ARHGEF35 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ARHGEF35 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of ARHGEF35 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of ARHGEF35 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of ARHGEF35 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.