{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Although several recent genomic and association studies have advanced our understanding of candidate genes involved in diverse human conditions – including primary ovarian insufficiency (1), prostate cancer (2), survival models for high‐dimensional censored data (3), tropical forest adaptation (4), dementia with Lewy bodies (5) and bone mineral density (6) – none of these reports provide functional insights into the role of the gene C2orf73. In these studies, authors identified and investigated novel candidate regions or genes (for example, GDF9 and several other regulators in (1), or the lncRNA PCAL7 in (2); also, candidate risk loci including SPTBN1, MARK3 and genomic regions impacting α‐synuclein binding in (5) and (6)) to elucidate disease mechanisms and pathways. However, C2orf73—the open reading frame on chromosome 2—was not a focus of any of these investigations, and no data regarding its expression, regulation, or functional impact were reported. Consequently, while these studies collectively demonstrate the power of high‐resolution genomic analyses and integrative network approaches to pinpoint candidate genes, the biological function of C2orf73 remains uncharacterized in this body of literature.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Further functional studies will be necessary to clarify whether C2orf73 has a role in any of these pathological processes or represents a disease‐irrelevant locus.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Citations:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "A Norling, A L Hirschberg, K A Rodriguez-Wallberg, et al. 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