CANT1 Gene

Name	calcium activated nucleotidase 1
Description	This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Calcium‐activated nucleotidase 1 (CANT1) is a multifunctional protein with dual roles in normal physiology and disease. Its well‐established enzymatic activity—requiring Ca²⁺ for substrate hydrolysis of nucleoside di‐ and triphosphates—contributes to proper proteoglycan synthesis in the cartilage extracellular matrix by promoting glycosaminoglycan assembly and regulating protein secretion within the Golgi/ER system (see."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": " This function is critical for normal endochondral ossification and chondrocyte differentiation, as evidenced by multiple studies showing that loss‐of‐function mutations in CANT1 underlie several skeletal dysplasias—including Desbuquois dysplasia type 1, Kim variant, and even forms of multiple epiphyseal dysplasia (MED) (see."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "7"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Biochemically, CANT1 (also known as hSCAN‑1) undergoes a Ca²⁺‑induced conformational change that is essential for its catalytic activity, a process that does not require additional posttranslational modifications such as glycosylation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": " Moreover, proper regulation of its expression influences protein quality control and secretion from the ER/Golgi, with deregulation leading to altered cellular degradation pathways."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the context of cancer, altered CANT1 expression has been linked to tumor biology. Elevated levels have been observed in prostate and renal cell carcinomas, where CANT1 appears to promote cell proliferation, migration, and survival. In lung cancers—including lung adenocarcinoma—promoter hypomethylation and overexpression of CANT1 correlate with more aggressive behavior, possibly through activation of NF‑κB signaling cascades."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "13"}]}, {"type": "t", "text": " In addition, in hepatocellular carcinoma models, in silico analyses have identified CANT1 among potential therapeutic targets."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Interestingly, beyond its role as a coding protein, transcripts originating from the CANT1 locus can also function as long non‐coding RNAs (lncRNAs) that exert tumor‐suppressive activities. In uveal melanoma, nuclear lncRNA variants of CANT1 have been shown to inhibit tumor growth and metastasis by modulating chromatin modifications and suppressing PI3Kγ expression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": " Furthermore, CANT1 can serve as a fusion partner in ETS gene rearrangements in prostate cancer, thereby contributing to disease pathogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, CANT1 plays a pivotal role in nucleotide hydrolysis that is essential for proteoglycan metabolism and proper skeletal development, while its dysregulation—through genetic mutations or altered expression—has important implications in various cancers. These diverse functions underline the potential of CANT1 both as a prognostic biomarker and as a candidate for targeted therapy in conditions ranging from skeletal dysplasias to malignancies.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Catherine Bui, Céline Huber, Beyhan Tuysuz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "XYLT1 mutations in Desbuquois dysplasia type 2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2014.01.020"}], "href": "https://doi.org/10.1016/j.ajhg.2014.01.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24581741"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24581741"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Céline Huber, Bénédicte Oulès, Marta Bertoli, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of CANT1 mutations in Desbuquois dysplasia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2009.10.001"}], "href": "https://doi.org/10.1016/j.ajhg.2009.10.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19853239"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19853239"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Tatsuya Furuichi, Jin Dai, Tae-Joon Cho, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CANT1 mutation is also responsible for Desbuquois dysplasia, type 2 and Kim variant."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Med Genet (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1136/jmg.2010.080226"}], "href": "https://doi.org/10.1136/jmg.2010.080226"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21037275"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21037275"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Chiara Paganini, Luca Monti, Rossella Costantini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.matbio.2018.11.002"}], "href": "https://doi.org/10.1016/j.matbio.2018.11.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30439444"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30439444"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Kazuki Kodama, Hiroaki Takahashi, Nobuyasu Oiji, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Open Bio (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/2211-5463.12859"}], "href": "https://doi.org/10.1002/2211-5463.12859"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32277574"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32277574"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Ankur Singh, Ok-Hwa Kim, Aritoshi Iida, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel CANT1 mutation in three Indian patients with Desbuquois dysplasia Kim type."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Med Genet (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ejmg.2014.11.006"}], "href": "https://doi.org/10.1016/j.ejmg.2014.11.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25486376"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25486376"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Hong-Dan Wang, Liang-Jie Guo, Zhan-Qi Feng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Orphanet J Rare Dis (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13023-020-01492-8"}], "href": "https://doi.org/10.1186/s13023-020-01492-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32907608"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32907608"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Deirdre M Murphy, Vasily V Ivanenkov, Terence L Kirley "}, {"type": "b", "children": [{"type": "t", "text": "Bacterial expression and characterization of a novel, soluble, calcium-binding, and calcium-activated human nucleotidase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochemistry (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/bi026763b"}], "href": "https://doi.org/10.1021/bi026763b"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12600208"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12600208"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Mingyan Yang, Terence L Kirley "}, {"type": "b", "children": [{"type": "t", "text": "Site-directed mutagenesis of human soluble calcium-activated nucleotidase 1 (hSCAN-1): identification of residues essential for enzyme activity and the Ca(2+)-induced conformational change."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochemistry (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/bi049565o"}], "href": "https://doi.org/10.1021/bi049565o"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15248776"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15248776"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Tito Calì, Laura Fedrizzi, Denis Ottolini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ca2+-activated nucleotidase 1, a novel target gene for the transcriptional repressor DREAM (downstream regulatory element antagonist modulator), is involved in protein folding and degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.304733"}], "href": "https://doi.org/10.1074/jbc.M111.304733"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22451650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22451650"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Josefine Gerhardt, Corinna Steinbrech, Oralea Büchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajpath.2010.12.046"}], "href": "https://doi.org/10.1016/j.ajpath.2010.12.046"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21435463"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21435463"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Fangfang Gao, Xiufeng Hu, Wenjing Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Bioengineered (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/21655979.2021.2003131"}], "href": "https://doi.org/10.1080/21655979.2021.2003131"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35068336"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35068336"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Qiwei Yao, Yilin Yu, Zhiping Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CANT1 serves as a potential prognostic factor for lung adenocarcinoma and promotes cell proliferation and invasion in vitro."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12885-022-09175-2"}], "href": "https://doi.org/10.1186/s12885-022-09175-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35090419"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35090419"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Chen Yang, Xiaowen Huang, Yan Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brief Bioinform (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/bib/bbaa164"}], "href": "https://doi.org/10.1093/bib/bbaa164"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32789496"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32789496"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Yue Xing, Xuyang Wen, Xia Ding, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Ther (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ymthe.2017.02.016"}], "href": "https://doi.org/10.1016/j.ymthe.2017.02.016"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28330694"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28330694"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Hongyan Ni, Peiwei Chai, Jie Yu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-020-2524-y"}], "href": "https://doi.org/10.1038/s41419-020-2524-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32366932"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32366932"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Bo Han, Rohit Mehra, Saravana M Dhanasekaran, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-08-2014"}], "href": "https://doi.org/10.1158/0008-5472.CAN-08-2014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18794152"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18794152"}]}]}]}
Synonyms	SCAN1, DBQD1, DBQD, SCAN-1, SHAPY, EDM7
Proteins	CANT1_HUMAN
NCBI Gene ID	124583
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

CANT1 has 7,337 functional associations with biological entities spanning 9 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 122 datasets.

Click the + buttons to view associations for CANT1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

CANT1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CANT1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of CANT1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of CANT1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of CANT1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of CANT1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CANT1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of CANT1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CANT1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CANT1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of CANT1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of CANT1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with CANT1 protein from the CCLE Cell Line Proteomics dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CANT1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of CANT1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of CANT1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with CANT1 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with CANT1 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing CANT1 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of CANT1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing CANT1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing CANT1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing CANT1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing CANT1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with CANT1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with CANT1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of CANT1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with CANT1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with CANT1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with CANT1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of CANT1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by CANT1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with CANT1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with CANT1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with CANT1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with CANT1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for CANT1 protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at CANT1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CANT1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of CANT1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing CANT1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.