CD151 Gene

HGNC Family	CD molecules (CD), Tetraspanins (TSPAN), Blood group antigens
Name	CD151 molecule (Raph blood group)
Description	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n CD151, a member of the tetraspanin family, plays a central role in regulating integrin‐dependent functions that control cell adhesion, migration, and signaling. By associating laterally with laminin‐binding integrins (α3β1, α6β1, α6β4, and α7β1), CD151 organizes specialized microdomains that potentiate integrin activation, enhance ligand binding, and facilitate integrin recycling. Its palmitoylation is critical for the assembly and stability of these complexes, thereby strengthening adhesion to extracellular matrices such as laminin (see."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Through these interactions, CD151 modulates key processes such as directional cell motility and persistent cell–matrix contacts. This activity promotes tumor cell invasion and metastasis in several cancers—including hepatocellular carcinoma, breast cancer, and melanoma—with overexpression correlating with poor clinical outcomes and aggressive disease behavior (see."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "9"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In vivo studies using CD151‐deficient models have revealed that absence of CD151 can lead to significant disruptions in tissue architecture and function. For example, CD151 ablation is associated with kidney basement membrane disorganization, altered podocyte function, and compromised cell migration, which underscores its importance in organ integrity and hemostasis (see."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "10", "end_ref": "13"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Furthermore, CD151 contributes to vascular and immune functions by modulating angiogenesis and stabilizing the interactions of adhesion molecules involved in leukocyte transendothelial migration (see"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "and."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": " Regulation of CD151 expression through microRNA‐dependent pathways and its involvement in epithelial–mesenchymal transition further illuminate its multifaceted role in tumor progression and metastasis (see"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": "and."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these findings establish CD151 as a master regulator of integrin‐mediated cellular functions. Its ability to strengthen adhesion, promote cell migration, and partake in pro‐invasive signaling cascades makes CD151 a key contributor to tumor metastasis and a promising target for therapeutic intervention.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiuwei Yang, Christoph Claas, Stine-Kathrein Kraeft, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.01-05-0275"}], "href": "https://doi.org/10.1091/mbc.01-05-0275"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11907260"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11907260"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xiuwei Yang, Oleg V Kovalenko, Wei Tang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Palmitoylation supports assembly and function of integrin-tetraspanin complexes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200404100"}], "href": "https://doi.org/10.1083/jcb.200404100"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15611341"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15611341"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Lotus M T Sterk, Cecile A W Geuijen, José G van den Berg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.115.6.1161"}], "href": "https://doi.org/10.1242/jcs.115.6.1161"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11884516"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11884516"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Ryoko Nishiuchi, Noriko Sanzen, Shigeyuki Nada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0409493102"}], "href": "https://doi.org/10.1073/pnas.0409493102"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15677332"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15677332"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hepatology (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/hep.22639"}], "href": "https://doi.org/10.1002/hep.22639"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19065669"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19065669"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Andries Zijlstra, John Lewis, Bernard Degryse, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Cell (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ccr.2008.01.031"}], "href": "https://doi.org/10.1016/j.ccr.2008.01.031"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18328426"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18328426"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CD151 amplifies signaling by integrin α6β1 to PI3K and induces the epithelial-mesenchymal transition in HCC cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gastroenterology (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1053/j.gastro.2011.02.008"}], "href": "https://doi.org/10.1053/j.gastro.2011.02.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21320503"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21320503"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Xiuwei H Yang, Andrea L Richardson, Maria I Torres-Arzayus, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-07-2949"}], "href": "https://doi.org/10.1158/0008-5472.CAN-07-2949"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18451146"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18451146"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "In-Kee Hong, Young-June Jin, Hee-Jung Byun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Homophilic interactions of Tetraspanin CD151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-Jun activation signaling pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M601209200"}], "href": "https://doi.org/10.1074/jbc.M601209200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16798740"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16798740"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Vanja Karamatic Crew, Nicholas Burton, Alexander Kagan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2004-04-1512"}], "href": "https://doi.org/10.1182/blood-2004-04-1512"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15265795"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15265795"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Norman Sachs, Maaike Kreft, Marius A van den Bergh Weerman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Kidney failure in mice lacking the tetraspanin CD151."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200603073"}], "href": "https://doi.org/10.1083/jcb.200603073"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17015618"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17015618"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Mark D Wright, Sean M Geary, Stephen Fitter, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of mice lacking the tetraspanin superfamily member CD151."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.24.13.5978-5988.2004"}], "href": "https://doi.org/10.1128/MCB.24.13.5978-5988.2004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15199151"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15199151"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Rosa M Baleato, Petrina L Guthrie, Marie-Claire Gubler, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2353/ajpath.2008.071149"}], "href": "https://doi.org/10.2353/ajpath.2008.071149"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18787104"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18787104"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Olga Barreiro, María Yáñez-Mó, Mónica Sala-Valdés, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2004-09-3606"}], "href": "https://doi.org/10.1182/blood-2004-09-3606"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15591117"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15591117"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Yoshito Takeda, Alexander R Kazarov, Catherine E Butterfield, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2006-08-041970"}], "href": "https://doi.org/10.1182/blood-2006-08-041970"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17023588"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17023588"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Peng-Fei Zhang, Fei Wang, Jing Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR-128/CD151 pathway in hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Physiol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcp.27095"}], "href": "https://doi.org/10.1002/jcp.27095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30132868"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30132868"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Himanshu Arora, Rehana Qureshi, Woong-Yang Park "}, {"type": "b", "children": [{"type": "t", "text": "miR-506 regulates epithelial mesenchymal transition in breast cancer cell lines."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0064273"}], "href": "https://doi.org/10.1371/journal.pone.0064273"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23717581"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23717581"}]}]}]}
Synonyms	PETA-3, MER2, TSPAN24, GP27, RAPH, SFA1
Proteins	CD151_HUMAN
NCBI Gene ID	977
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

CD151 has 9,413 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 122 datasets.

Click the + buttons to view associations for CD151 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

CD151 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by CD151 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CD151 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of CD151 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of CD151 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of CD151 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of CD151 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CD151 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of CD151 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CD151 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CD151 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of CD151 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of CD151 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of CD151 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with CD151 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with CD151 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CD151 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of CD151 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of CD151 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with CD151 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of CD151 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing CD151 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing CD151 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with CD151 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with CD151 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing CD151 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with CD151 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with CD151 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with CD151 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of CD151 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by CD151 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving CD151 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving CD151 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with CD151 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with CD151 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with CD151 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with CD151 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with CD151 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at CD151 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CD151 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of CD151 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.