COL27A1 Gene

HGNC Family	Collagens (COL)
Name	collagen, type XXVII, alpha 1
Description	This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Sep 2014]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n COL27A1 encodes the type XXVII collagen—a fibrillar collagen that is a critical structural component of the extracellular matrix in cartilage and several other tissues. Its primary function is to ensure proper chondrocyte organization and extracellular matrix assembly during chondrogenesis and endochondral ossification."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": " Transcription factors such as SOX9 and Lc‐Maf regulate its expression in chondrocytes, thereby ensuring proper growth plate architecture and the formation of a functional cartilage scaffold."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}, {"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Disruption of COL27A1 function—whether by mutations, deletions, or alternative splicing—compromises normal collagen deposition and leads to disorganization of the proliferative zone in the growth plate. Such alterations underlie skeletal dysplasias, most notably Steel syndrome, a disorder characterized by short stature, hip dysplasia, carpal coalitions, scoliosis, and other skeletal abnormalities."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "11"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In addition to its well‐established role in cartilage biology, COL27A1 has been implicated in other conditions. Genetic association studies have identified variants in this gene linked to neuropsychiatric disorders such as Tourette syndrome"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "and musculoskeletal soft tissue injuries like Achilles tendinopathy."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": " Furthermore, the COL27A1 locus also harbors microRNAs – notably miR-455 – whose dysregulation has been associated with pathologies including Alzheimer’s disease"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": ", suggesting that this genomic region may exert multifunctional effects beyond skeletal development.\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Together, these findings underscore the pivotal role of COL27A1 in establishing and maintaining the extracellular matrix framework necessary for proper cartilage formation and skeletal development, while also hinting at its broader implications in other clinical conditions when its normal function is perturbed.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "James M Pace, Marcella Corrado, Caterina Missero, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification, characterization and expression analysis of a new fibrillar collagen gene, COL27A1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0945-053x(03)00007-6"}], "href": "https://doi.org/10.1016/s0945-053x(03"}, {"type": "t", "text": "00007-6) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12714037"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12714037"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Elizabeth Jenkins, Jennie B Moss, James M Pace, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The new collagen gene COL27A1 contains SOX9-responsive enhancer elements."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.matbio.2005.02.004"}], "href": "https://doi.org/10.1016/j.matbio.2005.02.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15922909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15922909"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Darren A Plumb, Laila Ferrara, Tanja Torbica, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Collagen XXVII organises the pericellular matrix in the growth plate."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0029422"}], "href": "https://doi.org/10.1371/journal.pone.0029422"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22206015"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22206015"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Jaime L Mayo, Devin N Holden, Jeffery R Barrow, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The transcription factor Lc-Maf participates in Col27a1 regulation during chondrocyte maturation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2009.04.020"}], "href": "https://doi.org/10.1016/j.yexcr.2009.04.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19414009"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19414009"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Claudia Gonzaga-Jauregui, Candace N Gamble, Bo Yuan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in COL27A1 cause Steel syndrome and suggest a founder mutation effect in the Puerto Rican population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Hum Genet (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ejhg.2014.107"}], "href": "https://doi.org/10.1038/ejhg.2014.107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24986830"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24986830"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Claudia Gonzaga-Jauregui, Gozde Yesil, Harikiran Nistala, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional biology of the Steel syndrome founder allele and evidence for clan genomics derivation of COL27A1 pathogenic alleles worldwide."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Hum Genet (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41431-020-0632-x"}], "href": "https://doi.org/10.1038/s41431-020-0632-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32376988"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32376988"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Nesrin Gariballa, Afif Ben-Mahmoud, Makanko Komara, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel aberrant splice site mutation in COL27A1 is responsible for Steel syndrome and extension of the phenotype to include hearing loss."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Med Genet A (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ajmg.a.38153"}], "href": "https://doi.org/10.1002/ajmg.a.38153"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28322503"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28322503"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "S Kotabagi, H Shah, A Shukla, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Second family provides further evidence for causation of Steel syndrome by biallelic mutations in COL27A1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Genet (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cge.13006"}], "href": "https://doi.org/10.1111/cge.13006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28276056"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28276056"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": " Evie Kritioti, Athina Theodosiou, Nayia Nicolaou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "First reported case of Steel syndrome in the European population: A novel homozygous mutation in COL27A1 and review of the literature."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Med Genet (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ejmg.2020.103939"}], "href": "https://doi.org/10.1016/j.ejmg.2020.103939"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32360765"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32360765"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Louise Amlie-Wolf, Sue Moyer-Harasink, Ann-Marie Carr, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Three new patients with Steel syndrome and a Puerto Rican specific COL27A1 mutation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Med Genet A (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ajmg.a.61465"}], "href": "https://doi.org/10.1002/ajmg.a.61465"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31903681"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31903681"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Chisei Satoh, Tatsuro Kondoh, Hitomi Shimizu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Brothers with novel compound heterozygous mutations in COL27A1 causing dental and genital abnormalities."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Med Genet (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ejmg.2020.104125"}], "href": "https://doi.org/10.1016/j.ejmg.2020.104125"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33359165"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33359165"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "J M Scharf, D Yu, C A Mathews, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study of Tourette's syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Psychiatry (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/mp.2012.69"}], "href": "https://doi.org/10.1038/mp.2012.69"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22889924"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22889924"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Shiguo Liu, Xiaoxia Yu, Quanchen Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Support of positive association in family-based genetic analysis between COL27A1 and Tourette syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/srep12687"}], "href": "https://doi.org/10.1038/srep12687"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26235311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26235311"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Colleen J Saunders, Lize van der Merwe, Michael Posthumus, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Investigation of variants within the COL27A1 and TNC genes and Achilles tendinopathy in two populations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Orthop Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jor.22278"}], "href": "https://doi.org/10.1002/jor.22278"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23192621"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23192621"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Andrea Gibbon, Colleen J Saunders, Malcolm Collins, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Defining the molecular signatures of Achilles tendinopathy and anterior cruciate ligament ruptures: A whole-exome sequencing approach."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0205860"}], "href": "https://doi.org/10.1371/journal.pone.0205860"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30359423"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30359423"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Subodh Kumar, P Hemachandra Reddy "}, {"type": "b", "children": [{"type": "t", "text": "A New Discovery of MicroRNA-455-3p in Alzheimer's Disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Alzheimers Dis (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3233/JAD-190583"}], "href": "https://doi.org/10.3233/JAD-190583"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31524168"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31524168"}]}]}]}
Synonyms	STLS
Proteins	CORA1_HUMAN
NCBI Gene ID	85301
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

COL27A1 has 6,080 functional associations with biological entities spanning 9 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 114 datasets.

Click the + buttons to view associations for COL27A1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

COL27A1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of COL27A1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of COL27A1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of COL27A1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of COL27A1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of COL27A1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of COL27A1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of COL27A1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of COL27A1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of COL27A1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of COL27A1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with COL27A1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of COL27A1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of COL27A1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of COL27A1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with COL27A1 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with COL27A1 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of COL27A1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing COL27A1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing COL27A1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with COL27A1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with COL27A1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with COL27A1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with COL27A1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with COL27A1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with COL27A1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by COL27A1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DGIdb Drug Targets 2026	interacting drugs for COL27A1 protein from the DGIdb Drug Targets 2026 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with COL27A1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with COL27A1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with COL27A1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with COL27A1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with COL27A1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with COL27A1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at COL27A1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of COL27A1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of COL27A1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing COL27A1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with COL27A1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with COL27A1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with COL27A1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.