CORIN Gene

HGNC Family	Proteases, serine (PRSS)
Name	corin, serine peptidase
Description	This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Corin is a cardiac‐expressed type II transmembrane serine protease that plays a central role in cardiovascular homeostasis by converting the inactive pro–atrial natriuretic peptide (pro–ANP) into bioactive ANP, a hormone critical for natriuresis, vasodilation, and blood pressure regulation (5,2,14). Its catalytic activity depends on precise zymogen activation, regulated by proteolytic cleavage and post‐translational modifications, including N‐glycosylation and ectodomain shedding mediated by ADAM10, which serve to spatially restrict its activity and prevent excessive proteolysis (8,10,18). In addition, corin activation is facilitated by upstream convertases such as PCSK6, underscoring the multistep regulation required for proper natriuretic peptide processing (9). Genetic variants that impair corin’s zymogen activation—for example, the T555I/Q568P allele and mutations such as R539C—have been associated with deficient natriuretic peptide processing, salt‐sensitive hypertension, and cardiac hypertrophy, suggesting that corin deficiency contributes to the pathogenesis of hypertensive heart disease and heart failure (4,6,7,13,16,17). Beyond its classical role in the heart, corin is also expressed in the pregnant uterus where it promotes trophoblast invasion and uterine spiral artery remodeling, and reduced uterine corin expression has been linked to pre‐eclampsia (1). Moreover, altered corin expression has been implicated in kidney disorders associated with salt retention, signifying its broader role in sodium homeostasis (20). The promoter and domain organization of the corin gene provide further insight into its strict tissue‐specific expression and regulation, while the detection of soluble corin in plasma highlights its potential utility as a biomarker for heart failure and other cardiovascular disorders (5,14,15,19). Overall, these studies establish corin as a physiologically essential protease whose dysfunction due to genetic or post‐translational defects contributes to a spectrum of cardiovascular and pregnancy‐related pathologies.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "; \n (2)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "; \n (3)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": "; \n (4)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": "; \n (5)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "; \n (6)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": "; \n (7)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": "; \n (8)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": "; \n (9)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "; \n (10)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": "; \n (11)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": "; \n (12)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "; \n (13)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": "; \n (14)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "; \n (15)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "; \n (16)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": "; \n (17)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": "; \n (18)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "18"}]}, {"type": "t", "text": "; \n (19)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "19"}]}, {"type": "t", "text": "; \n (20)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "20"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yujie Cui, Wei Wang, Ningzheng Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature10897"}], "href": "https://doi.org/10.1038/nature10897"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22437503"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22437503"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Joyce C Y Chan, Ole Knudson, Faye Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hypertension in mice lacking the proatrial natriuretic peptide convertase corin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0407234102"}], "href": "https://doi.org/10.1073/pnas.0407234102"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15637153"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15637153"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Peter A Nigrovic, Daniel H D Gray, Tatiana Jones, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2353/ajpath.2008.080407"}], "href": "https://doi.org/10.2353/ajpath.2008.080407"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18988802"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18988802"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Daniel L Dries, Ronald G Victor, J Eduardo Rame, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.105.568881"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.105.568881"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16216958"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16216958"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Faye Wu, Wei Yan, Junliang Pan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M201503200"}], "href": "https://doi.org/10.1074/jbc.M201503200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11884416"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11884416"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "J Eduardo Rame, Mark H Drazner, Wendy Post, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hypertension (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/01.HYP.0000258566.95867.9e"}], "href": "https://doi.org/10.1161/01.HYP.0000258566.95867.9e"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17296875"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17296875"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Wei Wang, Xudong Liao, Koichi Fukuda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCRESAHA.108.177352"}], "href": "https://doi.org/10.1161/CIRCRESAHA.108.177352"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18669922"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18669922"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Sabine Knappe, Faye Wu, Mary Rose Masikat, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M309991200"}], "href": "https://doi.org/10.1074/jbc.M309991200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14559895"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14559895"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Shenghan Chen, Pengxiu Cao, Ningzheng Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PCSK6-mediated corin activation is essential for normal blood pressure."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.3920"}], "href": "https://doi.org/10.1038/nm.3920"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26259032"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26259032"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jingjing Jiang, Shannon Wu, Wei Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ectodomain shedding and autocleavage of the cardiac membrane protease corin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.185082"}], "href": "https://doi.org/10.1074/jbc.M110.185082"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21288900"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21288900"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Wei Wang, Jianzhong Shen, Yujie Cui, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Heart Fail (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCHEARTFAILURE.109.866822"}], "href": "https://doi.org/10.1161/CIRCHEARTFAILURE.109.866822"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19919978"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19919978"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Junliang Pan, Bernd Hinzmann, Wei Yan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genomic structures of the human and murine corin genes and functional GATA elements in their promoters."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M205686200"}], "href": "https://doi.org/10.1074/jbc.M205686200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12154094"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12154094"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Ningzheng Dong, Shenghan Chen, Wei Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin in clinical laboratory diagnostics."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Chim Acta (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cca.2011.10.032"}], "href": "https://doi.org/10.1016/j.cca.2011.10.032"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22093942"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22093942"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Ningzheng Dong, Chaodong Fang, Yizhi Jiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin mutation R539C from hypertensive patients impairs zymogen activation and generates an inactive alternative ectodomain fragment."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M112.411512"}], "href": "https://doi.org/10.1074/jbc.M112.411512"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23372161"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23372161"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Wei Wang, Yujie Cui, Jianzhong Shen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Salt-sensitive hypertension and cardiac hypertrophy in transgenic mice expressing a corin variant identified in blacks."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hypertension (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/HYPERTENSIONAHA.112.201244"}], "href": "https://doi.org/10.1161/HYPERTENSIONAHA.112.201244"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22987923"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22987923"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Inna P Gladysheva, Brian R Robinson, Aiilyan K Houng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Corin is co-expressed with pro-ANP and localized on the cardiomyocyte surface in both zymogen and catalytically active forms."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Cell Cardiol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yjmcc.2007.10.002"}], "href": "https://doi.org/10.1016/j.yjmcc.2007.10.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17996891"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17996891"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Tomoko Ichiki, Brenda K Huntley, John C Burnett "}, {"type": "b", "children": [{"type": "t", "text": "BNP molecular forms and processing by the cardiac serine protease corin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Adv Clin Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/b978-0-12-407680-8.00001-4"}], "href": "https://doi.org/10.1016/b978-0-12-407680-8.00001-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24015598"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24015598"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Danny Polzin, Henriette J Kaminski, Christian Kastner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Kidney Int (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ki.2010.197"}], "href": "https://doi.org/10.1038/ki.2010.197"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20613715"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20613715"}]}]}]}
Synonyms	PEE5, CRN, Lrp4, ATC2, TMPRSS10
Proteins	CORIN_HUMAN
NCBI Gene ID	10699
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

CORIN has 5,840 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 118 datasets.

Click the + buttons to view associations for CORIN from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

CORIN Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of CORIN gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of CORIN gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of CORIN gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of CORIN gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CORIN gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving CORIN protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of CORIN gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CORIN gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CORIN gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of CORIN gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of CORIN gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of CORIN gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with CORIN gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CORIN gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of CORIN gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of CORIN gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with CORIN gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with CORIN gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing CORIN protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing CORIN protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing CORIN protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing CORIN protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with CORIN protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with CORIN protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of CORIN gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with CORIN gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with CORIN gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with CORIN gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with CORIN gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by CORIN gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving CORIN gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving CORIN gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with CORIN gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with CORIN gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with CORIN gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with CORIN gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with CORIN gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at CORIN gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CORIN gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of CORIN gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.