DPF3 Gene

HGNC Family	Zinc fingers
Name	D4, zinc and double PHD fingers, family 3
Description	This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nDPF3 is a key component of the BAF (SWI/SNF) chromatin remodeling complex whose tandem plant homeodomain (PHD) fingers serve as “readers” of histone post‐translational modifications. Its PHD modules recognize acetylated lysine residues—most notably lysine 14 on histone H3—and can also bind methylated histones. These interactions allow DPF3 to function as an alternative to bromodomains in targeting modified chromatin, thereby facilitating gene transcription during critical developmental processes such as heart and muscle formation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its role as a histone mark reader, DPF3 links key transcription factor cascades to chromatin remodeling. It physically associates with components of the NF‐κB system—potentiating RelA/p50‐dependent transactivation—and is positively regulated by STAT5 signaling, thereby integrating extracellular stimuli with chromatin‐based transcriptional responses."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nDPF3 further exhibits context‐dependent functions in pathological settings. Under hypertrophic stimuli, the short isoform DPF3a becomes phosphorylated by casein kinase 2, triggering its interaction with transcriptional repressors (such as HEY) and effectively switching cardiac gene programs from repression to activation via recruitment of BRG1—events that underlie pathological cardiac hypertrophy. In oncogenic contexts, aberrant DPF3 expression has been linked to enhanced cell proliferation and migration. For instance, in breast cancer, downregulation of DPF3 is associated with increased tumor cell growth through activation of the JAK2/STAT3 pathway, while in renal cell carcinoma multiple studies demonstrate that elevated DPF3 levels facilitate oncogenic signaling (including via STAT3 and TGF‐β pathways), leading to increased cell survival and metastatic behavior."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "10"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its canonical role in chromatin modulation, DPF3 has been found to “moonlight” in the regulation of cell division and ciliogenesis. It dynamically localizes to centriolar satellites, centrosomes, and spindle structures during mitosis, where it is essential for stable kinetochore–microtubule attachments and proper chromosome alignment. Moreover, its presence at the base of primary cilia is required for the axoneme extension process, demonstrating an unexpected role in the formation of these sensory organelles."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nGenetic association studies have further implicated DPF3 in a spectrum of human conditions. Variants in DPF3 have been linked not only to alterations in sperm morphology and idiopathic male infertility but also to developmental disorders such as Hirschsprung's disease and differential susceptibility to infectious diseases like pulmonary tuberculosis. In addition, rare genetic variations involving DPF3 appear to contribute to familial breast cancer risk, underscoring the diverse and context‐dependent roles of this epigenetic regulator."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "17"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Martin Lange, Bogac Kaynak, Ulrike B Forster, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.471408"}], "href": "https://doi.org/10.1101/gad.471408"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18765789"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18765789"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Lei Zeng, Qiang Zhang, Side Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature09139"}], "href": "https://doi.org/10.1038/nature09139"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20613843"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20613843"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Weiguo Li, Anthony Zhao, Wolfram Tempel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Crystal structure of DPF3b in complex with an acetylated histone peptide."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Struct Biol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jsb.2016.07.001"}], "href": "https://doi.org/10.1016/j.jsb.2016.07.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27402533"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27402533"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Aya Ishizaka, Taketoshi Mizutani, Kazuyoshi Kobayashi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Double plant homeodomain (PHD) finger proteins DPF3a and -3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF-κB RelA/p50 heterodimer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.322792"}], "href": "https://doi.org/10.1074/jbc.M111.322792"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22334708"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22334708"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Marina Theodorou, Matthaios Speletas, Antigoni Mamara, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0076155"}], "href": "https://doi.org/10.1371/journal.pone.0076155"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24155890"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24155890"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Huanhuan Cui, Jenny Schlesinger, Sophia Schoenhals, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkv1244"}], "href": "https://doi.org/10.1093/nar/gkv1244"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26582913"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26582913"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Wei-Hao Lin, Wei-Gang Dai, Xiang-Dong Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Downregulation of DPF3 promotes the proliferation and motility of breast cancer cells through activating JAK2/STAT3 signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2019.04.170"}], "href": "https://doi.org/10.1016/j.bbrc.2019.04.170"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31076105"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31076105"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Leandro M Colli, Lea Jessop, Timothy A Myers, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2021.07.009"}], "href": "https://doi.org/10.1016/j.ajhg.2021.07.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34390653"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34390653"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Johanna Protze, Stephanie Naas, René Krüger, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2022.101699"}], "href": "https://doi.org/10.1016/j.jbc.2022.101699"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35148991"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35148991"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Huanhuan Cui, Hongyang Yi, Hongyu Bao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-022-32472-0"}], "href": "https://doi.org/10.1038/s41467-022-32472-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35945219"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35945219"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Giulia Verrillo, Anna Maria Obeid, Alexia Genco, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.261744"}], "href": "https://doi.org/10.1242/jcs.261744"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38661008"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38661008"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Carolyn R Hoyal, Stefan Kammerer, Richard B Roth, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Carcinog (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1477-3163-4-13"}], "href": "https://doi.org/10.1186/1477-3163-4-13"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16109180"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16109180"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Gülüm Kosova, James M Hotaling, Samuel Ohlander, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variants in DPF3 and DSCAML1 are associated with sperm morphology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Assist Reprod Genet (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10815-013-0140-9"}], "href": "https://doi.org/10.1007/s10815-013-0140-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24271036"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24271036"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Hang Liu, Yuanyuan Luo, Shuangshuang Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression profiles of HA117 and its neighboring gene DPF3 in different colon segments of Hirschsprung's disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Clin Exp Pathol (2014)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25120773"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25120773"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Shu-Yuan Liu, Chang-Jun Zhang, Hai-Ying Peng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Strong association of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "SLC1A1"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "DPF3"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " gene variants with idiopathic male infertility in Han Chinese."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Asian J Androl (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4103/1008-682X.178850"}], "href": "https://doi.org/10.4103/1008-682X.178850"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27232852"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27232852"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Youichi Sato, Chise Hasegawa, Atsushi Tajima, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of TUSC1 and DPF3 gene polymorphisms with male infertility."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Assist Reprod Genet (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10815-017-1052-x"}], "href": "https://doi.org/10.1007/s10815-017-1052-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28975488"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28975488"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Changchun Liu, Mingyue Chen, Jinpeng Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "DPF3 polymorphisms increased the risk of pulmonary tuberculosis in the Northwest Chinese Han population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gene (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.gene.2024.148617"}], "href": "https://doi.org/10.1016/j.gene.2024.148617"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38795855"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38795855"}]}]}]}
Synonyms	BAF45C, CERD4
Proteins	DPF3_HUMAN
NCBI Gene ID	8110
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

DPF3 has 6,179 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 115 datasets.

Click the + buttons to view associations for DPF3 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

DPF3 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of DPF3 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of DPF3 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of DPF3 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of DPF3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of DPF3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of DPF3 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of DPF3 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of DPF3 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of DPF3 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of DPF3 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of DPF3 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with DPF3 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with DPF3 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of DPF3 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of DPF3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of DPF3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of DPF3 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of DPF3 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing DPF3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing DPF3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with DPF3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with DPF3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of DPF3 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with DPF3 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with DPF3 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with DPF3 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with DPF3 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by DPF3 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with DPF3 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with DPF3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with DPF3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with DPF3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with DPF3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at DPF3 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of DPF3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of DPF3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing DPF3 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with DPF3 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with DPF3 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of DPF3 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.