EPB41L5 Gene

Name	erythrocyte membrane protein band 4.1 like 5
Description	Predicted to enable cytoskeletal protein binding activity and protein domain specific binding activity. Predicted to be involved in actomyosin structure organization. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic foregut morphogenesis; and mesoderm morphogenesis. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n EPB41L5 is a multifunctional FERM‐domain adaptor protein that integrates cell polarity, adhesion, and cytoskeletal dynamics in both developmental and pathological contexts. In epithelia, EPB41L5 is strongly induced during epithelial–mesenchymal transition (EMT) where it disrupts cell–cell adhesion by interacting with p120‐catenin to promote E‐cadherin internalization and, in parallel, binds paxillin to enhance integrin–mediated focal adhesion formation, thereby facilitating cell migration and invasion."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n Moreover, as a component of the Crumbs complex, EPB41L5 associates via its FERM domain with key polarity regulators such as MPP5, thereby contributing to the establishment and maintenance of apicobasal membrane organization in mature epithelial cells."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the context of cancer, aberrantly high expression of EPB41L5 is linked to a mesenchymal and invasive phenotype. Elevated EPB41L5 levels correlate with increased metastatic potential and poor prognosis in diverse tumor types, including tongue and esophageal squamous cell carcinomas, as well as non‐small cell lung cancers where its expression is derepressed by exosomal long non‐coding RNAs."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}, {"type": "fg_f", "ref": "3"}, {"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n EPB41L5 is also essential for proper cell–matrix adhesion in specialized cells. In podocytes, it is highly enriched in focal adhesion complexes where it orchestrates integrin site maturation and extracellular matrix deposition to maintain glomerular basement membrane integrity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Regulation of EPB41L5 itself is tightly controlled. For instance, the ubiquitin ligase MIB1 binds and ubiquitinates EPB41L5, which influences its degradation and thereby modulates epithelial cell morphology and neural progenitor delamination."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}, {"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": " In addition, a circRNA derived from EPB41L5 (circ‐EPB41L5) has been shown to act as a molecular sponge to regulate oncogenic signaling via RhoC and AKT in glioblastoma."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Finally, EPB41L5 (also known as Lulu) enhances myosin‐II activation to drive apical constriction and cell shape changes during epithelial morphogenesis"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": ", and genetic variations near the EPB41L5 locus may contribute to clinical outcomes in settings such as radiation‐induced vision loss"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "as well as membranous nephropathy via perturbations in competing endogenous RNA networks."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": " Together, these studies underscore EPB41L5 as a pivotal molecular hub that bridges cell adhesion, polarity, and cytoskeletal remodeling, with its dysregulation promoting EMT, aberrant migration, and disease progression.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mariko Hirano, Shigeru Hashimoto, Shigenobu Yonemura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200712086"}], "href": "https://doi.org/10.1083/jcb.200712086"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18794329"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18794329"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Mi-Hyeon Jeong, Soo-Yeon Park, Seung-Hyun Lee, et al. "}, {"type": "b", "children": [{"type": "t", "text": "EPB41L5 Mediates TGFβ-Induced Metastasis of Gastric Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Cancer Res (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1078-0432.CCR-18-2959"}], "href": "https://doi.org/10.1158/1078-0432.CCR-18-2959"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30814110"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30814110"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "ShiHao Bao, ZhiQi Ji, Mo Shi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2021.153682"}], "href": "https://doi.org/10.1016/j.prp.2021.153682"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34784520"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34784520"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Small GTPases (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/21541248.2016.1249043"}], "href": "https://doi.org/10.1080/21541248.2016.1249043"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27754741"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27754741"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ilse Gosens, Alessandro Sessa, Anneke I den Hollander, et al. "}, {"type": "b", "children": [{"type": "t", "text": "FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2007.08.025"}], "href": "https://doi.org/10.1016/j.yexcr.2007.08.025"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17920587"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17920587"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Sascha E Dho, Nancy Silva-Gagliardi, Fabio Morgese, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-48902-x"}], "href": "https://doi.org/10.1038/s41598-019-48902-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31462741"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31462741"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Yutaro Otsuka, Hiroki Sato, Tsukasa Oikawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Commun Signal (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12964-016-0151-0"}], "href": "https://doi.org/10.1186/s12964-016-0151-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27871329"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27871329"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Dongming Wu, Shihua Deng, Li Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-021-04004-z"}], "href": "https://doi.org/10.1038/s41419-021-04004-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34285192"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34285192"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Christoph Schell, Manuel Rogg, Martina Suhm, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1617004114"}], "href": "https://doi.org/10.1073/pnas.1617004114"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28536193"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28536193"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jasmin I Maier, Manuel Rogg, Martin Helmstädter, et al. "}, {"type": "b", "children": [{"type": "t", "text": "EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2021.108883"}], "href": "https://doi.org/10.1016/j.celrep.2021.108883"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33761352"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33761352"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Miho Matsuda, Kinneret Rand, Greg Palardy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Epb41l5 competes with Delta as a substrate for Mib1 to coordinate specification and differentiation of neurons."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.138743"}], "href": "https://doi.org/10.1242/dev.138743"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27510968"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27510968"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "James Saller, Shabnam Seydafkan, Mohammad Shahid, et al. "}, {"type": "b", "children": [{"type": "t", "text": "EPB41L5 is Associated With the Metastatic Potential of Low-grade Pancreatic Neuroendocrine Tumors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Genomics Proteomics (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21873/cgp.20136"}], "href": "https://doi.org/10.21873/cgp.20136"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31467225"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31467225"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Hiroyuki Nakajima, Takuji Tanoue "}, {"type": "b", "children": [{"type": "t", "text": "Epithelial cell shape is regulated by Lulu proteins via myosin-II."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.057752"}], "href": "https://doi.org/10.1242/jcs.057752"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20103536"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20103536"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Thanos D Papakostas, Margaux A Morrison, Anne Marie Lane, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic Risk Factors for Radiation Vasculopathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Invest Ophthalmol Vis Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1167/iovs.17-22791"}], "href": "https://doi.org/10.1167/iovs.17-22791"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29625478"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29625478"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Guangyu Zhou, Nan Jiang, Wenlong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Biomarker Identification in Membranous Nephropathy Using a Long Non-coding RNA-Mediated Competitive Endogenous RNA Network."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Interdiscip Sci (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12539-021-00466-z"}], "href": "https://doi.org/10.1007/s12539-021-00466-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34472046"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34472046"}]}]}]}
Synonyms	YMO1, BE37, YRT
Proteins	E41L5_HUMAN
NCBI Gene ID	57669
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

EPB41L5 has 7,960 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 114 datasets.

Click the + buttons to view associations for EPB41L5 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

EPB41L5 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of EPB41L5 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of EPB41L5 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of EPB41L5 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of EPB41L5 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of EPB41L5 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of EPB41L5 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of EPB41L5 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of EPB41L5 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of EPB41L5 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of EPB41L5 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of EPB41L5 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of EPB41L5 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with EPB41L5 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with EPB41L5 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of EPB41L5 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of EPB41L5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of EPB41L5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing EPB41L5 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of EPB41L5 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing EPB41L5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing EPB41L5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing EPB41L5 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing EPB41L5 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with EPB41L5 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with EPB41L5 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of EPB41L5 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with EPB41L5 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with EPB41L5 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with EPB41L5 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of EPB41L5 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by EPB41L5 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with EPB41L5 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with EPB41L5 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with EPB41L5 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with EPB41L5 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at EPB41L5 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of EPB41L5 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of EPB41L5 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing EPB41L5 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of EPB41L5 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.