{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A review of the 32 abstracts provided—from studies addressing topics as diverse as hypoxia‐regulated endocytosis, oncogenic STAT3 signaling, osteoclastogenesis, hematological trait genetics, developmental and regenerative biology, to large‐scale genomic and proteomic surveys—\n reveals a broad spectrum of cellular, molecular, and organismal processes being investigated."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "32"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Notably, none of these studies specifically investigate or delineate a role for FAM234A. Although FAM234A has been annotated as a member of the FAM234 gene family, its function is not discussed or implicated in any of the aforementioned reports. In contrast, these abstracts provide detailed insights into processes such as membrane protein internalization under hypoxic conditions, oncogenic signaling cascades, cell differentiation, hematological trait variation, and evolutionary dynamics—but they do not offer evidence to assign a cellular or physiological function to FAM234A.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, while the collection of studies spans a wide range of biomedical research areas, they do not contribute functional information regarding FAM234A. As its biological role remains undefined based on the current abstract set, targeted investigations will be necessary to uncover any contributions of FAM234A to cellular function or disease.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "E Bourseau-Guilmain, J A Menard, E Lindqvist, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms11371"}], "href": "https://doi.org/10.1038/ncomms11371"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27094744"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27094744"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Melanie Si Yan Tan, Edwin Sandanaraj, Yuk Kien Chong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A STAT3-based gene signature stratifies glioma patients for targeted therapy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-019-11614-x"}], "href": "https://doi.org/10.1038/s41467-019-11614-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31399589"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31399589"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Takahiro Itou, Natalia Maldonado, Iwao Yamada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cystathionine γ-lyase accelerates osteoclast differentiation: identification of a novel regulator of osteoclastogenesis by proteomic analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/ATVBAHA.113.302576"}], "href": "https://doi.org/10.1161/ATVBAHA.113.302576"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24357058"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24357058"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Unknown Authors "}, {"type": "b", "children": [{"type": "t", "text": "Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.3607"}], "href": "https://doi.org/10.1038/ng.3607"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27399967"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27399967"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Caroline M Van Daele, Julio A Chirinos, Marc L De Buyzere, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Feasibility and agreement of a novel combined echocardiographic method to measure global longitudinal strain and strain rate compared to speckle tracking and tissue Doppler imaging."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Cardiol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/00015385.2019.1565661"}], "href": "https://doi.org/10.1080/00015385.2019.1565661"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31070525"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31070525"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Laura Heireman, Ariane Luyckx, Katrien De Schynkel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Detection of a Large Novel α-Thalassemia Deletion in an Autochthonous Belgian Family."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hemoglobin (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/03630269.2019.1625786"}], "href": "https://doi.org/10.1080/03630269.2019.1625786"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31223040"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31223040"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Joshua D Backman, Alexander H Li, Anthony Marcketta, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Exome sequencing and analysis of 454,787 UK Biobank participants."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41586-021-04103-z"}], "href": "https://doi.org/10.1038/s41586-021-04103-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34662886"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34662886"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Carol C Cheung, Penny Barnes, Gilbert Bigras, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Fit-For-Purpose PD-L1 Biomarker Testing For Patient Selection in Immuno-Oncology: Guidelines For Clinical Laboratories From the Canadian Association of Pathologists-Association Canadienne Des Pathologistes (CAP-ACP)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Appl Immunohistochem Mol Morphol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/PAI.0000000000000800"}], "href": "https://doi.org/10.1097/PAI.0000000000000800"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31584451"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31584451"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Benjamin J Ravenhill, Usheer Kanjee, Ambroise Ahouidi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Quantitative comparative analysis of human erythrocyte surface proteins between individuals from two genetically distinct populations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Commun Biol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s42003-019-0596-y"}], "href": "https://doi.org/10.1038/s42003-019-0596-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31552303"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31552303"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "John S Waye, Barry Eng, Meredith Hanna, et al. "}, {"type": "b", "children": [{"type": "t", "text": "α"}, {"type": "a", "children": [{"type": "t", "text": "sup"}], "href": "sup"}, {"type": "t", "text": "0"}, {"type": "a", "children": [{"type": "t", "text": "/sup"}], "href": "/sup"}, {"type": "t", "text": "-Thalassemia Due to a 90.7 kb Deletion (- -"}, {"type": "a", "children": [{"type": "t", "text": "sup"}], "href": "sup"}, {"type": "t", "text": "NFLD"}, {"type": "a", "children": [{"type": "t", "text": "/sup"}], "href": "/sup"}, {"type": "t", "text": ")."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hemoglobin (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/03630269.2017.1369987"}], "href": "https://doi.org/10.1080/03630269.2017.1369987"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28838269"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28838269"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "William J Astle, Heather Elding, Tao Jiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cell.2016.10.042"}], "href": "https://doi.org/10.1016/j.cell.2016.10.042"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27863252"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27863252"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Paula Tríbulo, María Belen Rabaglino, Martin Bonet Bo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dickkopf-related protein 1 is a progestomedin acting on the bovine embryo during the morula-to-blastocyst transition to program trophoblast elongation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-48374-z"}], "href": "https://doi.org/10.1038/s41598-019-48374-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31413296"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31413296"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Jimena Grosso, Diego Baldo, Darío Cardozo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Early ontogeny and sequence heterochronies in Leiuperinae frogs (Anura: Leptodactylidae)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0218733"}], "href": "https://doi.org/10.1371/journal.pone.0218733"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31246982"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31246982"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Segun Fatumo, Tommy Carstensen, Oyekanmi Nashiru, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fgene.2019.00334"}], "href": "https://doi.org/10.3389/fgene.2019.00334"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31080455"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31080455"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Shinji Goto, Maximillian A Rogers, Mark C Blaser, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Standardization of Human Calcific Aortic Valve Disease "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "in vitro"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " Modeling Reveals Passage-Dependent Calcification."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Cardiovasc Med (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fcvm.2019.00049"}], "href": "https://doi.org/10.3389/fcvm.2019.00049"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31041314"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31041314"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Zhao Chen, Hua Tang, Rehan Qayyum, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddt087"}], "href": "https://doi.org/10.1093/hmg/ddt087"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23446634"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23446634"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Dong-Hyun Kim, Jinwoo Lee, Jinju Bae, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mechanical Analysis of Ceramic/Polymer Composite with Mesh-Type Lightweight Design Using Binder-Jet 3D Printing."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Materials (Basel) (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ma11101941"}], "href": "https://doi.org/10.3390/ma11101941"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30314331"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30314331"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Ryong Nam Kim, Hyeong-Gon Moon, Wonshik Han, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Perspective Insight into Future Potential Fusion Gene Transcript Biomarker Candidates in Breast Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms19020502"}], "href": "https://doi.org/10.3390/ijms19020502"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29414922"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29414922"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Wei Zhao, Asif Rasheed, Emmi Tikkanen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.3943"}], "href": "https://doi.org/10.1038/ng.3943"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28869590"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28869590"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Pedro H Prete, Igor Cizauskas, Antonio D Brescovit "}, {"type": "b", "children": [{"type": "t", "text": "Three new species of the spider genus "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "Plato"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and the new genus "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "Cuacuba"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " from caves of the states of Pará and Minas Gerais, Brazil (Araneae, Theridiosomatidae)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zookeys (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3897/zookeys.753.20805"}], "href": "https://doi.org/10.3897/zookeys.753.20805"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29736139"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29736139"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Hyun Jung Park, Guohua Jin, Luay Nakhleh "}, {"type": "b", "children": [{"type": "t", "text": "Bootstrap-based support of HGT inferred by maximum parsimony."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Evol Biol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2148-10-131"}], "href": "https://doi.org/10.1186/1471-2148-10-131"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20444286"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20444286"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Douglas B Rusch, Aaron L Halpern, Granger Sutton, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.0050077"}], "href": "https://doi.org/10.1371/journal.pbio.0050077"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17355176"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17355176"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Runa M Grimholt, Petter Urdal, Olav Klingenberg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Rapid and reliable detection of α-globin copy number variations by quantitative real-time PCR."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Hematol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/2052-1839-14-4"}], "href": "https://doi.org/10.1186/2052-1839-14-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24456650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24456650"}]}, {"type": "r", "ref": 24, "children": [{"type": "t", "text": "Yan Zhang, Vadim N Gladyshev "}, {"type": "b", "children": [{"type": "t", "text": "Trends in selenium utilization in marine microbial world revealed through the analysis of the global ocean sampling (GOS) project."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.1000095"}], "href": "https://doi.org/10.1371/journal.pgen.1000095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18551170"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18551170"}]}, {"type": "r", "ref": 25, "children": [{"type": "t", "text": "Steven Bassnett, Phillip A Wilmarth, Larry L David "}, {"type": "b", "children": [{"type": "t", "text": "The membrane proteome of the mouse lens fiber cell."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Vis (2009)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19956408"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19956408"}]}, {"type": "r", "ref": 26, "children": [{"type": "t", "text": "Izabela Makałowska, Chiao-Feng Lin, Krisitina Hernandez "}, {"type": "b", "children": [{"type": "t", "text": "Birth and death of gene overlaps in vertebrates."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Evol Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2148-7-193"}], "href": "https://doi.org/10.1186/1471-2148-7-193"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17939861"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17939861"}]}, {"type": "r", "ref": 27, "children": [{"type": "t", "text": "Vidushi S Patel, Steven J B Cooper, Janine E Deakin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Biol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1741-7007-6-34"}], "href": "https://doi.org/10.1186/1741-7007-6-34"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18657265"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18657265"}]}, {"type": "r", "ref": 28, "children": [{"type": "t", "text": "Shannon J Williamson, Douglas B Rusch, Shibu Yooseph, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samples."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0001456"}], "href": "https://doi.org/10.1371/journal.pone.0001456"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18213365"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18213365"}]}, {"type": "r", "ref": 29, "children": [{"type": "t", "text": "Chris L Dupont, Douglas B Rusch, Shibu Yooseph, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "ISME J (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ismej.2011.189"}], "href": "https://doi.org/10.1038/ismej.2011.189"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22170421"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22170421"}]}, {"type": "r", "ref": 30, "children": [{"type": "t", "text": "Juan C Opazo, G Tyler Butts, Mariana F Nery, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Whole-genome duplication and the functional diversification of teleost fish hemoglobins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Evol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/molbev/mss212"}], "href": "https://doi.org/10.1093/molbev/mss212"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22949522"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22949522"}]}, {"type": "r", "ref": 31, "children": [{"type": "t", "text": "D Hinz, G Seumois, A M Gholami, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Exp Allergy (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cea.12692"}], "href": "https://doi.org/10.1111/cea.12692"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26662458"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26662458"}]}, {"type": "r", "ref": 32, "children": [{"type": "t", "text": "M Rogers-Bald, R G Sargent, P E Bryant "}, {"type": "b", "children": [{"type": "t", "text": "Production of chromatid breaks by single dsb: evidence supporting the signal model."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Radiat Biol (2000)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/095530000138970"}], "href": "https://doi.org/10.1080/095530000138970"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "10665954"}], "href": "https://pubmed.ncbi.nlm.nih.gov/10665954"}]}]}]}