FBN3 Gene

Name fibrillin 3
Description This gene encodes a memebr of the fibrillin protein family. Fibrillins are extracellular matrix molecules that assemble into microfibrils in many connective tissues. This gene is most highly expressed in fetal tissues and its protein product is localized to extracellular microfibrils of developing skeletal elements, skin, lung, kidney, and skeletal muscle. This gene is potentially involved in Weill-Marchesani syndrome. [provided by RefSeq, Mar 2016]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent genetic mapping has implicated the fibrillin‐3 (FBN3) gene in polycystic ovary syndrome (PCOS), with linkage of markers in intron 55 (D19S884) suggesting a role in ovarian pathophysiology and endocrine regulation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In addition, investigations into FBN3 polymorphisms have extended to disorders of abnormal skeletal growth, such as adolescent idiopathic scoliosis, indicating that genetic variation in FBN3 may influence overall growth patterns."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Detailed single nucleotide polymorphism analyses in PCOS cohorts have shown that although FBN3 messenger RNA levels are considerably lower than those of related fibrillin proteins in adult ovarian tissue, specific alleles (e.g., the D19S884 A8 allele) are associated with altered circulating transforming growth factor‐β (TGF‐β) isoforms."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Immunohistochemical studies further demonstrate that fibrillin‐3 localizes to a restricted domain within the specialized perifollicular stroma of transitional follicles—suggesting a role in the primordial to primary follicle transition—and that its reduced presence is a common feature in polycystic ovaries."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nDuring early human development, FBN3 is temporally expressed in multiple tissues—including perichondrium, skin, and developing bronchi—implying both overlapping and distinct roles compared with other fibrillin family members."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " In the fetal ovary, the dynamic expression of fibrillin‐3 in stromal compartments coincides with critical stages of follicle formation and appears to influence TGF‐β bioavailability, a pathway that may predispose to the PCOS phenotype later in life."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": " Moreover, genetic studies in women with PCOS have linked FBN3 risk variants to metabolic alterations—including perturbed insulin secretion and endogenous glucose production—thereby extending the functional impact of FBN3 beyond reproductive development."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nCorroborative case–control studies and meta-analyses have further reinforced an association between FBN3 markers (notably the D19S884 A8 allele) and an increased susceptibility to PCOS across diverse populations."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": " Whole-exome sequencing in familial PCOS cases has also highlighted FBN3 as a candidate gene harboring rare, high-effect variants that may contribute to the complex etiology of the syndrome."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": " Finally, emerging evidence extends the significance of FBN3 to craniofacial development; specific FBN3 single nucleotide polymorphisms have been linked with skeletal malocclusion, suggesting that FBN3 function is important not only for ovarian and metabolic homeostasis but also for the regulation of extracellular matrix architecture in craniofacial and connective tissues."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Margrit Urbanek, Susan Sam, Richard S Legro, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Endocrinol Metab (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/jc.2007-0761"}], "href": "https://doi.org/10.1210/jc.2007-0761"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17785364"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17785364"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xing-Bing Cao, Yong Qiu, Xu-Sheng Qiu "}, {"type": "b", "children": [{"type": "t", "text": "[FBN3 gene polymorphisms in adolescent idiopathic scoliosis patients]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Yi Xue Za Zhi (2008)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19192405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19192405"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Mark J Prodoehl, Nicholas Hatzirodos, Helen F Irving-Rodgers, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic and gene expression analyses of the polycystic ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Hum Reprod (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/molehr/gap072"}], "href": "https://doi.org/10.1093/molehr/gap072"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19692420"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19692420"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Nazia Raja-Khan, Allen R Kunselman, Laurence M Demers, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Fertil Steril (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.fertnstert.2010.05.047"}], "href": "https://doi.org/10.1016/j.fertnstert.2010.05.047"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20630504"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20630504"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "C Diana Jordan, Sandra D Bohling, Noe L Charbonneau, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Fibrillins in adult human ovary and polycystic ovary syndrome: is fibrillin-3 affected in PCOS?"}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Histochem Cytochem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1369/jhc.2010.956615"}], "href": "https://doi.org/10.1369/jhc.2010.956615"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20855553"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20855553"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Laetitia Sabatier, Nicolai Miosge, Dirk Hubmacher, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Fibrillin-3 expression in human development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.matbio.2010.10.003"}], "href": "https://doi.org/10.1016/j.matbio.2010.10.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20970500"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20970500"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Nicholas Hatzirodos, Rosemary A Bayne, Helen F Irving-Rodgers, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Linkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FASEB J (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1096/fj.11-181099"}], "href": "https://doi.org/10.1096/fj.11-181099"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21411746"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21411746"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Sudha K Yalamanchi, Susan Sam, Maria O Cardenas, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Obesity (Silver Spring) (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/oby.2011.400"}], "href": "https://doi.org/10.1038/oby.2011.400"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22301903"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22301903"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Guang-bin Xie, Pei Xu, Ye-na Che, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Microsatellite polymorphism in the fibrillin 3 gene and susceptibility to PCOS: a case-control study and meta-analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Reprod Biomed Online (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.rbmo.2012.10.014"}], "href": "https://doi.org/10.1016/j.rbmo.2012.10.014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23265956"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23265956"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Cengiz Karakaya, Aylin Pelin Çil, Kaya Bilguvar, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Further delineation of familial polycystic ovary syndrome (PCOS) via whole-exome sequencing: PCOS-related rare FBN3 and FN1 gene variants are identified."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Obstet Gynaecol Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/jog.15187"}], "href": "https://doi.org/10.1111/jog.15187"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35141985"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35141985"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Adina Maria Topârcean, Arina Acatrinei, Ioana Rusu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic Insights into Skeletal Malocclusion: The Role of the FBN3 "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "rs7351083"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " SNP in the Romanian Population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Medicina (Kaunas) (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/medicina60071061"}], "href": "https://doi.org/10.3390/medicina60071061"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "39064490"}], "href": "https://pubmed.ncbi.nlm.nih.gov/39064490"}]}]}]}
Proteins FBN3_HUMAN
NCBI Gene ID 84467
API
Download Associations
Predicted Functions View FBN3's ARCHS4 Predicted Functions.
Co-expressed Genes View FBN3's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View FBN3's ARCHS4 Predicted Functions.

Functional Associations

FBN3 has 2,264 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 79 datasets.

Click the + buttons to view associations for FBN3 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles tissues with high or low expression of FBN3 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of FBN3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq tissue samples with high or low expression of FBN3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles tissues with high or low expression of FBN3 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of FBN3 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of FBN3 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of FBN3 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of FBN3 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of FBN3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of FBN3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing FBN3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores 2025 cellular components containing FBN3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with FBN3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with FBN3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with FBN3 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
CTD Gene-Chemical Interactions chemicals interacting with FBN3 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
dbGAP Gene-Trait Associations traits associated with FBN3 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
DeepCoverMOA Drug Mechanisms of Action small molecule perturbations with high or low expression of FBN3 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by FBN3 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with FBN3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with FBN3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with FBN3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
DisGeNET Gene-Phenotype Associations phenotypes associated with FBN3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at FBN3 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of FBN3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of FBN3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GAD Gene-Disease Associations diseases associated with FBN3 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
GAD High Level Gene-Disease Associations diseases associated with FBN3 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with FBN3 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing FBN3 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of FBN3 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GlyGen Glycosylated Proteins ligands (chemical) binding FBN3 protein from the GlyGen Glycosylated Proteins dataset.
GO Cellular Component Annotations 2015 cellular components containing FBN3 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by FBN3 gene from the curated GO Molecular Function Annotations 2015 dataset.
GTEx eQTL 2025 SNPs regulating expression of FBN3 gene from the GTEx eQTL 2025 dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of FBN3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Gene Expression Profiles 2023 tissues with high or low expression of FBN3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of FBN3 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
GWASdb SNP-Disease Associations diseases associated with FBN3 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
GWASdb SNP-Phenotype Associations phenotypes associated with FBN3 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of FBN3 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HMDB Metabolites of Enzymes interacting metabolites for FBN3 protein from the curated HMDB Metabolites of Enzymes dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of FBN3 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of FBN3 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of FBN3 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of FBN3 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
HuGE Navigator Gene-Phenotype Associations phenotypes associated with FBN3 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for FBN3 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of FBN3 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of FBN3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles cell lines with FBN3 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of FBN3 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
LOCATE Curated Protein Localization Annotations cellular components containing FBN3 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain FBN3 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MiRTarBase microRNA Targets microRNAs targeting FBN3 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of FBN3 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
NURSA Protein Complexes protein complexs containing FBN3 protein recovered by IP-MS from the NURSA Protein Complexes dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for FBN3 from the Pathway Commons Protein-Protein Interactions dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of FBN3 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PFOCR Pathway Figure Associations 2023 pathways involving FBN3 protein from the PFOCR Pathway Figure Associations 2023 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving FBN3 protein from the Wikipathways PFOCR 2024 dataset.
Reactome Pathways 2014 pathways involving FBN3 protein from the Reactome Pathways dataset.
Reactome Pathways 2024 pathways involving FBN3 protein from the Reactome Pathways 2024 dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of FBN3 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at FBN3 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of FBN3 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of FBN3 gene from the RummaGEO Gene Perturbation Signatures dataset.
TargetScan Predicted Conserved microRNA Targets microRNAs regulating expression of FBN3 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
TargetScan Predicted Nonconserved microRNA Targets microRNAs regulating expression of FBN3 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of FBN3 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of FBN3 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of FBN3 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of FBN3 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 tissues with high expression of FBN3 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with FBN3 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with FBN3 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.
Virus MINT Protein-Viral Protein Interactions interacting viral proteins for FBN3 from the Virus MINT Protein-Viral Protein Interactions dataset.
Virus MINT Protein-Virus Interactions viruses interacting with FBN3 from the Virus MINT Protein-Virus Interactions dataset.
WikiPathways Pathways 2024 pathways involving FBN3 protein from the WikiPathways Pathways 2024 dataset.