FBXW11 Gene

HGNC Family	F-boxes (FBX), WD repeat domain containing (WDR)
Name	F-box and WD repeat domain containing 11
Description	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n FBXW11 is an F‐box protein component of the SCF (Skp1–Cullin–F‐box) E3 ubiquitin ligase complex that orchestrates the proteolytic turnover of key signaling regulators across diverse cellular contexts. Several studies have demonstrated that FBXW11 controls the stability of critical substrates to modulate pathways involved in development, tumorigenesis, and cellular homeostasis. For instance, FBXW11 regulates the levels of PTEN isoforms, thereby acting as a molecular rheostat in carcinogenesis"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", and facilitates the polyubiquitination and subsequent degradation of substrates such as RAPGEF2 to influence cell adhesion and cytokinesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " In lymphocytic leukemia cells, elevated FBXW11 levels promote cell proliferation and cell cycle progression by concomitantly activating NF‑κB and β‑catenin/TCF signaling"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": ", while epigenetic alterations affecting FBXW11 have been observed in head and neck carcinomas."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": " Moreover, de novo variants in FBXW11 have been linked to developmental anomalies—including defects in brain, jaw, and digit formation"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": ", and copy-number gains involving FBXW11 are proposed as candidate drivers of holoprosencephaly and preaxial polydactyly."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Its dysregulation is also evident in tumor transcriptomes such as those from pediatric high‐grade gliomas"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": ", and in colorectal cancer, FBXW11 overexpression enhances stem cell–like properties and liver metastasis by modulating HIC1-mediated SIRT1 expression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": " In addition, FBXW11 plays a central role in the regulation of the Wnt/β‑catenin pathway by contributing to the destruction complex that limits β‑catenin accumulation in the absence of Wnt signaling."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": " In the neurological context, enhanced FBXW11 activity in microglia promotes ASK1 ubiquitination, thereby aberrantly activating NF‑κB and MAPK cascades and contributing to neuroinflammatory processes in Alzheimer’s disease."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": " Moreover, FBXW11 targets metabolic regulators such as Lipin‑1 for degradation, further underscoring its role in maintaining metabolic homeostasis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": " In osteosarcoma, FBXW11 is directly targeted by miR‑221, and this regulatory interaction promotes oncogenic Wnt signaling to enhance proliferation and inhibit apoptosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": " Finally, FBXW11 has been implicated in the regulation of activation-induced cytidine deaminase (AID) through formation of a complex with CUL7, thereby influencing antibody class switching."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": " Collectively, these findings highlight FBXW11 as a versatile regulator of protein turnover whose context-dependent functions impact cell signaling, development, and disease progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}, {"type": "fg_f", "ref": "4"}, {"type": "fg_f", "ref": "9"}, {"type": "fg_f", "ref": "3"}, {"type": "fg_f", "ref": "1"}, {"type": "fg_f", "ref": "5"}, {"type": "fg_f", "ref": "8"}, {"type": "fg_fs", "start_ref": "10", "end_ref": "13"}, {"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Shao-Ming Shen, Cheng Zhang, Meng-Kai Ge, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Cell Biol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41556-019-0409-z"}], "href": "https://doi.org/10.1038/s41556-019-0409-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31685992"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31685992"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Tai Young Kim, Priscila F Siesser, Kent L Rossman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00857-14"}], "href": "https://doi.org/10.1128/MCB.00857-14"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25332235"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25332235"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Lina Wang, Wenli Feng, Xiao Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-018-0440-1"}], "href": "https://doi.org/10.1038/s41419-018-0440-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29555946"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29555946"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Jarosław Paluszczak, Dorota Wiśniewska, Magdalena Kostrzewska-Poczekaj, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic significance of the methylation of Wnt pathway antagonists-CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling-ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Oral Investig (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00784-016-1946-5"}], "href": "https://doi.org/10.1007/s00784-016-1946-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27553089"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27553089"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Richard J Holt, Rodrigo M Young, Berta Crespo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2019.07.005"}], "href": "https://doi.org/10.1016/j.ajhg.2019.07.005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31402090"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31402090"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "David A Koolen, Jos Herbergs, Joris A Veltman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Hum Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10038-006-0010-8"}], "href": "https://doi.org/10.1007/s10038-006-0010-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16865294"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16865294"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Patricia C Sanchez-Diaz, Judy C Chang, Emily S Moses, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0176879"}], "href": "https://doi.org/10.1371/journal.pone.0176879"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28472177"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28472177"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Jing Yao, Jun Yang, Zhe Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "FBXW11 contributes to stem-cell-like features and liver metastasis through regulating HIC1-mediated SIRT1 transcription in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-021-04185-7"}], "href": "https://doi.org/10.1038/s41419-021-04185-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34642302"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34642302"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Masashi Kitazawa, Tomohisa Hatta, Koji Ogawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Determination of Rate-Limiting Factor for Formation of Beta-Catenin Destruction Complexes Using Absolute Protein Quantification."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Proteome Res (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/acs.jproteome.7b00305"}], "href": "https://doi.org/10.1021/acs.jproteome.7b00305"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28810742"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28810742"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jingjie Sun, Xiaodong Qin, Xinyan Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "FBXW11 deletion alleviates Alzheimer's disease by reducing neuroinflammation and amyloid-β plaque formation via repression of ASK1 signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2020.12.081"}], "href": "https://doi.org/10.1016/j.bbrc.2020.12.081"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33640602"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33640602"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Kenji Ishimoto, Ayaka Hayase, Fumiko Kumagai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Degradation of human Lipin-1 by BTRC E3 ubiquitin ligase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2017.04.159"}], "href": "https://doi.org/10.1016/j.bbrc.2017.04.159"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28483528"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28483528"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Qingzhu Zhang, Xuelian Yin, Yi Zhang "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-221 Promotes Cell Proliferation and Inhibits Apoptosis in Osteosarcoma Cells by Directly Targeting FBXW11 and Regulating Wnt Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arch Med Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.arcmed.2020.10.017"}], "href": "https://doi.org/10.1016/j.arcmed.2020.10.017"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33131925"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33131925"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Yuewen Luo, Yang Liu, Liyang Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1900125"}], "href": "https://doi.org/10.4049/jimmunol.1900125"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31092637"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31092637"}]}]}]}
Synonyms	BTRCP2, FBW11, FBXW1B, BTRC2, FBW1B
Proteins	FBW1B_HUMAN
NCBI Gene ID	23291
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

FBXW11 has 6,578 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 121 datasets.

Click the + buttons to view associations for FBXW11 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

FBXW11 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by FBXW11 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of FBXW11 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of FBXW11 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of FBXW11 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of FBXW11 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of FBXW11 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of FBXW11 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of FBXW11 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of FBXW11 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of FBXW11 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of FBXW11 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of FBXW11 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of FBXW11 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with FBXW11 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with FBXW11 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of FBXW11 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of FBXW11 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of FBXW11 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with FBXW11 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing FBXW11 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of FBXW11 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing FBXW11 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing FBXW11 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing FBXW11 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with FBXW11 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing FBXW11 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of FBXW11 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with FBXW11 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with FBXW11 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with FBXW11 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with FBXW11 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with FBXW11 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with FBXW11 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with FBXW11 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at FBXW11 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of FBXW11 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of FBXW11 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing FBXW11 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of FBXW11 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with FBXW11 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.