GPR27 Gene

HGNC Family G protein-coupled receptors
Name G protein-coupled receptor 27
Description GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n G‐protein–coupled receptor 27 (GPR27), also known as SREB1, is a highly conserved orphan receptor that was originally cloned from brain tissue (see."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Although it is predominantly expressed in the central nervous system, GPR27 is also found in metabolic tissues such as pancreatic β‐cells, where emerging evidence indicates that it positively modulates insulin promoter activity and glucose‐stimulated insulin secretion by likely coupling to the Gq/11 pathway and increasing inositol phosphate production."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Whole‐body knockout studies in mice and zebrafish further support this role by demonstrating that loss of GPR27 leads to reduced insulin mRNA levels, impaired insulin signaling, disrupted glucose homeostasis, and alterations in lipid metabolism—such as elevations in medium‐chain acylcarnitines that are indicative of insulin resistance."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": " In addition, GPR27 appears to have relevance for oncogenesis since overexpression in hepatocellular carcinoma cells enhances proliferation via activation of the MAPK/ERK signaling cascade, while epigenetic silencing (for example, hypermethylation) has been observed in cervical cancer."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": " Genomic studies have also identified that deletions encompassing the GPR27 coding region are associated with neurodevelopmental deficits, underscoring its potential contribution to intellectual disability."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": " Finally, the discovery of unique features in its genetic organization—including overlapping reading frames (“matreshkas”)—and the development of selective surrogate agonists further suggest that GPR27 may have multifaceted roles in both metabolism and cellular proliferation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "10", "end_ref": "12"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "B F O'Dowd, T Nguyen, A Marchese, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Discovery of three novel G-protein-coupled receptor genes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genomics (1998)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/geno.1998.5095"}], "href": "https://doi.org/10.1006/geno.1998.5095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "9479505"}], "href": "https://pubmed.ncbi.nlm.nih.gov/9479505"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "M Matsumoto, T Saito, J Takasaki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2000)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/bbrc.2000.2829"}], "href": "https://doi.org/10.1006/bbrc.2000.2829"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "10833454"}], "href": "https://pubmed.ncbi.nlm.nih.gov/10833454"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Gregory M Ku, Zachary Pappalardo, Chun Chieh Luo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.1002449"}], "href": "https://doi.org/10.1371/journal.pgen.1002449"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22253604"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22253604"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Nadine Dupuis, Céline Laschet, Delphine Franssen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "β"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": "-Arrestin 2 Recruitment."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Pharmacol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1124/mol.116.107714"}], "href": "https://doi.org/10.1124/mol.116.107714"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28314853"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28314853"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Deeksha G Chopra, Nicholas Yiv, Thomas G Hennings, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deletion of Gpr27 in vivo reduces insulin mRNA but does not result in diabetes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-020-62358-4"}], "href": "https://doi.org/10.1038/s41598-020-62358-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32221326"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32221326"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Anjali K Nath, Junyan Ma, Zsu-Zsu Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FASEB J (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1096/fj.201901466R"}], "href": "https://doi.org/10.1096/fj.201901466R"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31914600"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31914600"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Hongxv Wang, Danyu Du, Jianwen Huang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GPR27 Regulates Hepatocellular Carcinoma Progression via MAPK/ERK Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Manag Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2147/CMAR.S335749"}], "href": "https://doi.org/10.2147/CMAR.S335749"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35330739"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35330739"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Malin Lando, Christina S Fjeldbo, Saskia M Wilting, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Epigenetics (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/15592294.2015.1085140"}], "href": "https://doi.org/10.1080/15592294.2015.1085140"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26291246"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26291246"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Erwin Petek, Christian Windpassinger, Burkhard Simma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Molecular characterisation of a 15 Mb constitutional de novo interstitial deletion of chromosome 3p in a boy with developmental delay and congenital anomalies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Hum Genet (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10038-003-0023-5"}], "href": "https://doi.org/10.1007/s10038-003-0023-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12836054"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12836054"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Thanigaimalai Pillaiyar, Francesca Rosato, Monika Wozniak, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Med Chem (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ejmech.2021.113777"}], "href": "https://doi.org/10.1016/j.ejmech.2021.113777"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34454125"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34454125"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Alp Bayrak, Julien Hanson, Stefan Laufer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Super-conserved receptors expressed in the brain: biology and medicinal chemistry efforts."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Future Med Chem (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4155/fmc-2022-0006"}], "href": "https://doi.org/10.4155/fmc-2022-0006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35535715"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35535715"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Sebastien Ribrioux, Adrian Brüngger, Birgit Baumgarten, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Genomics (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2164-9-122"}], "href": "https://doi.org/10.1186/1471-2164-9-122"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18325113"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18325113"}]}]}]}
Synonyms SREB1
Proteins GPR27_HUMAN
NCBI Gene ID 2850
API
Download Associations
Predicted Functions View GPR27's ARCHS4 Predicted Functions.
Co-expressed Genes View GPR27's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View GPR27's ARCHS4 Predicted Functions.

Functional Associations

GPR27 has 2,825 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 80 datasets.

Click the + buttons to view associations for GPR27 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Achilles Cell Line Gene Essentiality Profiles cell lines with fitness changed by GPR27 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles tissues with high or low expression of GPR27 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
BioGPS Cell Line Gene Expression Profiles cell lines with high or low expression of GPR27 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of GPR27 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
BioGPS Mouse Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of GPR27 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of GPR27 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of GPR27 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of GPR27 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of GPR27 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of GPR27 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of GPR27 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing GPR27 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with GPR27 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with GPR27 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of GPR27 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with GPR27 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
CTD Gene-Disease Associations diseases associated with GPR27 gene/protein from the curated CTD Gene-Disease Associations dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by GPR27 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Experimental Gene-Disease Association Evidence Scores 2025 diseases associated with GPR27 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with GPR27 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with GPR27 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with GPR27 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at GPR27 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of GPR27 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of GPR27 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells PubMedIDs of publications reporting gene signatures containing GPR27 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of GPR27 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing GPR27 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of GPR27 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GO Biological Process Annotations 2015 biological processes involving GPR27 gene from the curated GO Biological Process Annotations 2015 dataset.
GO Cellular Component Annotations 2015 cellular components containing GPR27 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by GPR27 gene from the curated GO Molecular Function Annotations 2015 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by GPR27 gene from the curated GO Molecular Function Annotations 2023 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by GPR27 gene from the curated GO Molecular Function Annotations 2025 dataset.
GTEx eQTL 2025 SNPs regulating expression of GPR27 gene from the GTEx eQTL 2025 dataset.
GTEx Tissue Gene Expression Profiles 2023 tissues with high or low expression of GPR27 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
GTEx Tissue-Specific Aging Signatures tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of GPR27 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of GPR27 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of GPR27 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of GPR27 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for GPR27 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of GPR27 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of GPR27 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of GPR27 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles cell lines with GPR27 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of GPR27 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain GPR27 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MGI Mouse Phenotype Associations 2023 phenotypes of transgenic mice caused by GPR27 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset.
MiRTarBase microRNA Targets microRNAs targeting GPR27 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of GPR27 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
MoTrPAC Rat Endurance Exercise Training tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the MoTrPAC Rat Endurance Exercise Training dataset.
NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles drug perturbations changing expression of GPR27 gene from the NIBR DRUG-seq U2OS MoA Box dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of GPR27 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations gene perturbations changing expression of GPR27 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PFOCR Pathway Figure Associations 2023 pathways involving GPR27 protein from the PFOCR Pathway Figure Associations 2023 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving GPR27 protein from the Wikipathways PFOCR 2024 dataset.
Reactome Pathways 2024 pathways involving GPR27 protein from the Reactome Pathways 2024 dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of GPR27 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at GPR27 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of GPR27 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of GPR27 gene from the RummaGEO Gene Perturbation Signatures dataset.
Tabula Sapiens Gene-Cell Associations cell types with high or low expression of GPR27 gene relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of GPR27 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of GPR27 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of GPR27 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 tissues with high expression of GPR27 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with GPR27 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with GPR27 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.
WikiPathways Pathways 2014 pathways involving GPR27 protein from the Wikipathways Pathways 2014 dataset.
WikiPathways Pathways 2024 pathways involving GPR27 protein from the WikiPathways Pathways 2024 dataset.