GTSE1 Gene

Name	G-2 and S-phase expressed 1
Description	The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n GTSE1 (G2 and S phase‐expressed 1) is a cell cycle–regulated protein that exerts multifaceted oncogenic functions. It plays a central role in cell cycle progression by facilitating transitions through the S and G2/M phases and, in doing so, contributes to proper mitotic spindle dynamics and chromosome congression. In several studies, GTSE1 has been shown to interact directly with microtubules and, via its plus‐end tracking activity, to inhibit the microtubule depolymerase MCAK—thereby ensuring accurate spindle orientation and genomic stability during mitosis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In addition, GTSE1 modulates key tumor suppressor pathways by interacting with and shuttling p53 out of the nucleus to promote its degradation. This negative regulation of p53 activity occurs via direct binding through its C‐terminal region and requires an intact nuclear export signal and functional MDM2, thereby diminishing p53‐dependent apoptosis and contributing to chemoresistance."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "8"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Overexpression of GTSE1 has been documented in a wide range of human cancers—including hepatocellular carcinoma, breast, prostate, lung, gastric, osteosarcoma, acral melanoma, and cervical cancers—where it is associated with enhanced proliferation, increased migratory and invasive capacities, and poorer clinical outcomes. Mechanistically, GTSE1 promotes epithelial‐to‐mesenchymal transition (EMT) and activates oncogenic signaling pathways such as AKT/mTOR and SP1/FOXM1, while its deregulated expression also contributes to resistance against chemotherapeutic agents like cisplatin by facilitating DNA damage repair and by reducing apoptosis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "9", "end_ref": "19"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Furthermore, GTSE1 expression is modulated by noncoding RNAs, as illustrated by studies in neuroblastoma and colon cancer where altered levels of specific micro‐ and long noncoding RNAs impact GTSE1 expression and, consequently, tumor cell migration and metastatic potential."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "20"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these findings position GTSE1 as a pivotal oncogenic driver that integrates cell cycle regulation, microtubule dynamics, and p53 pathway modulation to promote tumor progression and chemoresistance. Its multifaceted roles across diverse cancer types make GTSE1 a promising prognostic marker and therapeutic target."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "22"}, {"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Shweta Bendre, Arnaud Rondelet, Conrad Hall, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.201606081"}], "href": "https://doi.org/10.1083/jcb.201606081"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27881713"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27881713"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Aaron R Tipton, Jonathan D Wren, John R Daum, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.201610012"}], "href": "https://doi.org/10.1083/jcb.201610012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28821562"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28821562"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Divya Singh, Nadine Schmidt, Franziska Müller, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Curr Biol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cub.2020.11.040"}], "href": "https://doi.org/10.1016/j.cub.2020.11.040"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33333009"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33333009"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Arnaud Rondelet, Yu-Chih Lin, Divya Singh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.201907083"}], "href": "https://doi.org/10.1083/jcb.201907083"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31932847"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31932847"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "X Shawn Liu, Hongchang Li, Bing Song, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Rep (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/embor.2010.90"}], "href": "https://doi.org/10.1038/embor.2010.90"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20577264"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20577264"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Martin Monte, Roberta Benetti, Giacomo Buscemi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M302902200"}], "href": "https://doi.org/10.1074/jbc.M302902200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12750368"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12750368"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Martin Monte, Roberta Benetti, Licio Collavin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "hGTSE-1 expression stimulates cytoplasmic localization of p53."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M311123200"}], "href": "https://doi.org/10.1074/jbc.M311123200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14707141"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14707141"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Débora Rosa Bublik, Massimiliano Scolz, Gianluca Triolo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human GTSE-1 regulates p21(CIP1/WAF1) stability conferring resistance to paclitaxel treatment."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M109.045948"}], "href": "https://doi.org/10.1074/jbc.M109.045948"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20018861"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20018861"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Xiaojuan Wu, Hongbo Wang, Yifan Lian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-05311-2"}], "href": "https://doi.org/10.1038/s41598-017-05311-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28698581"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28698581"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Fen Lin, Yu-Jie Xie, Xin-Ke Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Clin Cancer Res (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13046-019-1157-4"}], "href": "https://doi.org/10.1186/s13046-019-1157-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30961661"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30961661"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Vinod Vijay Subhash, Shi Hui Tan, Woei Loon Tan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 expression represses apoptotic signaling and confers cisplatin resistance in gastric cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12885-015-1550-0"}], "href": "https://doi.org/10.1186/s12885-015-1550-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26209226"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26209226"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Yongchang Zheng, Yue Shi, Si Yu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Anal Cell Pathol (Amst) (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2019/1038069"}], "href": "https://doi.org/10.1155/2019/1038069"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32082966"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32082966"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Tianxiao Xu, Meng Ma, Zhihong Chi, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Lab Invest (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41374-020-00510-4"}], "href": "https://doi.org/10.1038/s41374-020-00510-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33328578"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33328578"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Tian Tian, Enpei Zhang, Fei Fei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Up-regulation of GTSE1 lacks a relationship with clinical data in lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Asian Pac J Cancer Prev (2011)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22292647"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22292647"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Chaofan Xie, Wei Xiang, Huiyong Shen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Orthop Surg Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13018-021-02859-8"}], "href": "https://doi.org/10.1186/s13018-021-02859-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34876170"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34876170"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Wenting Guo, Jing Zhu, Yuan Zhu, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0051259"}], "href": "https://doi.org/10.1371/journal.pone.0051259"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23236459"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23236459"}]}]}]}
Synonyms	B99
Proteins	GTSE1_HUMAN
NCBI Gene ID	51512
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

GTSE1 has 9,777 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 130 datasets.

Click the + buttons to view associations for GTSE1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

GTSE1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by GTSE1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of GTSE1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of GTSE1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of GTSE1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of GTSE1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of GTSE1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of GTSE1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of GTSE1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of GTSE1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of GTSE1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of GTSE1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of GTSE1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with GTSE1 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with GTSE1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with GTSE1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of GTSE1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of GTSE1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of GTSE1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of GTSE1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing GTSE1 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of GTSE1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing GTSE1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing GTSE1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing GTSE1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing GTSE1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with GTSE1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with GTSE1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of GTSE1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with GTSE1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with GTSE1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with GTSE1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of GTSE1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by GTSE1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with GTSE1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with GTSE1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with GTSE1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with GTSE1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at GTSE1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of GTSE1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of GTSE1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.