HMMR Gene

HGNC Family	CD molecules (CD)
Name	hyaluronan-mediated motility receptor (RHAMM)
Description	The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Human HMMR (hyaluronan‐mediated motility receptor), also known as RHAMM, is emerging as a multifunctional protein that critically modulates tumor cell behavior. Genetic network studies have identified HMMR as a centrosomal component that associates with key factors such as BRCA1, with germline variation at the HMMR locus being linked to an increased risk of breast cancer in BRCA1 mutation carriers."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " At the cell surface, HMMR partners with receptors such as CD44 to mediate interactions with hyaluronan and thereby promote cell motility, invasion, and downstream signaling through pathways including ERK1/2 and FAK; these actions contribute to aggressive features in breast cancer, fibrosarcoma, and glioblastoma."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "3", "end_ref": "6"}]}, {"type": "t", "text": " Intracellularly, HMMR plays a key role in controlling mitotic spindle integrity and microtubule stability; dysregulation of its expression leads to centrosomal abnormalities, aberrant cell cycle progression, and mitotic errors that are further modulated by p53 and associated spindle assembly factors."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "10"}]}, {"type": "t", "text": " Moreover, HMMR has been recognized as an immunogenic tumor‐associated antigen; vaccination studies targeting HMMR peptides in hematologic malignancies have demonstrated the capacity to elicit specific anti-tumor immune responses."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": " In addition, in experimental arthritis models, loss of CD44 function is compensated by HMMR, leading to enhanced cell migration and exacerbated inflammation"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": ", while in glioma and astrocytoma models, its expression correlates with aggressive cellular proliferation and migratory behavior."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": " In the context of solid tumors such as bladder, prostate, and endometrial cancers, elevated HMMR levels correlate with higher tumor grade, metastatic potential, and poorer clinical outcomes, thus representing both a prognostic biomarker and a therapeutic target."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "16", "end_ref": "18"}]}, {"type": "t", "text": " Finally, studies in aggressive fibromatosis have shown that loss of HMMR decreases tumor formation by reducing the proliferation of cells with sparse cell–cell contacts"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "19"}]}, {"type": "t", "text": ", further underscoring its role in controlling cell proliferation. Collectively, these findings characterize HMMR as a critical mediator of cell motility, mitotic regulation, and immune recognition whose dysregulation contributes to tumor progression and metastasis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}, {"type": "fg_f", "ref": "20"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Miguel Angel Pujana, Jing-Dong J Han, Lea M Starita, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Network modeling links breast cancer susceptibility and centrosome dysfunction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.2007.2"}], "href": "https://doi.org/10.1038/ng.2007.2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17922014"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17922014"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Christopher A Maxwell, Javier Benítez, Laia Gómez-Baldó, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.1001199"}], "href": "https://doi.org/10.1371/journal.pbio.1001199"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22110403"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22110403"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Zhongyuan Wang, Yanping Wu, Haifeng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1319190110"}], "href": "https://doi.org/10.1073/pnas.1319190110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24367099"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24367099"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Sara R Hamilton, Shireen F Fard, Frouz F Paiwand, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M702078200"}], "href": "https://doi.org/10.1074/jbc.M702078200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17392272"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17392272"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Katerina Kouvidi, Aikaterini Berdiaki, Dragana Nikitovic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.275875"}], "href": "https://doi.org/10.1074/jbc.M111.275875"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21914806"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21914806"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Jessica Tilghman, Hao Wu, Yingying Sang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-13-2103"}], "href": "https://doi.org/10.1158/0008-5472.CAN-13-2103"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24710409"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24710409"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Christopher Alan Maxwell, James McCarthy, Eva Turley "}, {"type": "b", "children": [{"type": "t", "text": "Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?"}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.022038"}], "href": "https://doi.org/10.1242/jcs.022038"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18354082"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18354082"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Christopher A Maxwell, Jonathan J Keats, Andrew R Belch, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2005)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15705883"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15705883"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Sindy Sohr, Kurt Engeland "}, {"type": "b", "children": [{"type": "t", "text": "RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Cycle (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/cc.7.21.7014"}], "href": "https://doi.org/10.4161/cc.7.21.7014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18971636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18971636"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Cornelia Tolg, Sara R Hamilton, Lyndsey Morningstar, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.121491"}], "href": "https://doi.org/10.1074/jbc.M110.121491"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20558733"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20558733"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Michael Schmitt, Anita Schmitt, Markus T Rojewski, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2007-07-099366"}], "href": "https://doi.org/10.1182/blood-2007-07-099366"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17978170"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17978170"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Jochen Greiner, Mark Ringhoffer, Masanori Taniguchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Receptor for hyaluronan acid-mediated motility (RHAMM) is a new immunogenic leukemia-associated antigen in acute and chronic myeloid leukemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Hematol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0301-472x(02)00874-3"}], "href": "https://doi.org/10.1016/s0301-472x(02"}, {"type": "t", "text": "00874-3) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12225794"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12225794"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Shlomo Nedvetzki, Erez Gonen, Nathalie Assayag, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: a different interpretation of redundancy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0407378102"}], "href": "https://doi.org/10.1073/pnas.0407378102"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15596723"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15596723"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Y Akiyama, S Jung, B Salhia, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hyaluronate receptors mediating glioma cell migration and proliferation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurooncol (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1023/a:1012297132047"}], "href": "https://doi.org/10.1023/a:1012297132047"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11716065"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11716065"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Dahis Manzanares, Maria-Elena Monzon, Rashmin C Savani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Apical oxidative hyaluronan degradation stimulates airway ciliary beating via RHAMM and RON."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Respir Cell Mol Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1165/rcmb.2006-0413OC"}], "href": "https://doi.org/10.1165/rcmb.2006-0413OC"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17395888"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17395888"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Mario W Kramer, Diogo O Escudero, Soum D Lokeshwar, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cncr.25565"}], "href": "https://doi.org/10.1002/cncr.25565"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20960509"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20960509"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Kilian M Gust, Matthias D Hofer, Sven R Perner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neoplasia (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1593/neo.09694"}], "href": "https://doi.org/10.1593/neo.09694"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19724689"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19724689"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "D T Rein, K Roehrig, T Schöndorf, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of the hyaluronan receptor RHAMM in endometrial carcinomas suggests a role in tumour progression and metastasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer Res Clin Oncol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00432-003-0415-0"}], "href": "https://doi.org/10.1007/s00432-003-0415-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12712331"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12712331"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Cornelia Tolg, Raymoond Poon, Riccardo Fodde, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.onc.1206811"}], "href": "https://doi.org/10.1038/sj.onc.1206811"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14534534"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14534534"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Ambrose Jong, Chun-Hua Wu, Ignacio Gonzales-Gomez, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hyaluronic acid receptor CD44 deficiency is associated with decreased Cryptococcus neoformans brain infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M112.353375"}], "href": "https://doi.org/10.1074/jbc.M112.353375"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22418440"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22418440"}]}]}]}
Synonyms	CD168, IHABP, RHAMM
Proteins	HMMR_HUMAN
NCBI Gene ID	3161
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

HMMR has 10,223 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 119 datasets.

Click the + buttons to view associations for HMMR from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

HMMR Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by HMMR gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HMMR gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of HMMR gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of HMMR gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of HMMR gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HMMR gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of HMMR gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HMMR gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HMMR gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of HMMR gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of HMMR gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with HMMR gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with HMMR protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with HMMR gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HMMR gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of HMMR gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of HMMR gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of HMMR gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing HMMR protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing HMMR protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing HMMR protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing HMMR protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with HMMR protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with HMMR protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with HMMR gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with HMMR gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with HMMR gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with HMMR gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of HMMR protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by HMMR gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with HMMR gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with HMMR gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with HMMR gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with HMMR gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for HMMR protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at HMMR gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HMMR gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of HMMR gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing HMMR from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with HMMR gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.