| Name | heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene |
| Description | HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90AA2 is a cytosolic HSP90 protein. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]). See HSP90AA1 (MIM 140571) for further information on HSP90 proteins.[supplied by OMIM, Aug 2008] |
| Synonyms | HSPCAL3, HSP90ALPHA, HSP90AA2 |
| Proteins | HS902_HUMAN |
| NCBI Gene ID | 3324 |
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| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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HSP90AA2P has 1,108 functional associations with biological entities spanning 6 categories (molecular profile, chemical, functional term, phrase or reference, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 13 datasets.
Click the + buttons to view associations for HSP90AA2P from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of HSP90AA2P gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of HSP90AA2P gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| CTD Gene-Chemical Interactions | chemicals interacting with HSP90AA2P gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
| GeneRIF Biological Term Annotations | biological terms co-occuring with HSP90AA2P gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of HSP90AA2P gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of HSP90AA2P gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of HSP90AA2P gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving HSP90AA2P gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by HSP90AA2P gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| Hub Proteins Protein-Protein Interactions | interacting hub proteins for HSP90AA2P from the curated Hub Proteins Protein-Protein Interactions dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain HSP90AA2P protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for HSP90AA2P from the Pathway Commons Protein-Protein Interactions dataset. | |
| Sanger Dependency Map Cancer Cell Line Proteomics | cell lines associated with HSP90AA2P protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset. | |
