HSP90AB4P Gene

Name heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
Description Predicted to enable ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]
Synonyms HSP90BD
Proteins H90B4_HUMAN
NCBI Gene ID 664618
API
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Predicted Functions View HSP90AB4P's ARCHS4 Predicted Functions.
Co-expressed Genes View HSP90AB4P's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View HSP90AB4P's ARCHS4 Predicted Functions.

Functional Associations

HSP90AB4P has 917 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for HSP90AB4P from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of HSP90AB4P gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of HSP90AB4P gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of HSP90AB4P gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing HSP90AB4P protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of HSP90AB4P gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
CTD Gene-Chemical Interactions chemicals interacting with HSP90AB4P gene/protein from the curated CTD Gene-Chemical Interactions dataset.
DeepCoverMOA Drug Mechanisms of Action small molecule perturbations with high or low expression of HSP90AB4P protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at HSP90AB4P gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of HSP90AB4P gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of HSP90AB4P gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GO Biological Process Annotations 2023 biological processes involving HSP90AB4P gene from the curated GO Biological Process Annotations 2023 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by HSP90AB4P gene from the curated GO Molecular Function Annotations 2023 dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of HSP90AB4P gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of HSP90AB4P gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of HSP90AB4P gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of HSP90AB4P gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MGI Mouse Phenotype Associations 2023 phenotypes of transgenic mice caused by HSP90AB4P gene mutations from the MGI Mouse Phenotype Associations 2023 dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for HSP90AB4P from the Pathway Commons Protein-Protein Interactions dataset.
ProteomicsDB Cell Type and Tissue Protein Expression Profiles cell types and tissues with high or low expression of HSP90AB4P protein relative to other cell types and tissues from the ProteomicsDB Cell Type and Tissue Protein Expression Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at HSP90AB4P gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
Sanger Dependency Map Cancer Cell Line Proteomics cell lines associated with HSP90AB4P protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of HSP90AB4P gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.