HGNC Family | Immunoglobulins (IG) |
Name | immunoglobulin lambda constant 2 (Kern-Oz- marker) |
Description | Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025] |
Proteins | LAC2_HUMAN |
NCBI Gene ID | 3538 |
API | |
Download Associations | |
Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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IGLC2 has 897 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.
Click the + buttons to view associations for IGLC2 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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CellMarker Gene-Cell Type Associations | cell types associated with IGLC2 gene from the CellMarker Gene-Cell Type Associations dataset. | |
ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of IGLC2 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
ChEA Transcription Factor Targets | transcription factors binding the promoter of IGLC2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing IGLC2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
CTD Gene-Chemical Interactions | chemicals interacting with IGLC2 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with IGLC2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
GDSC Cell Line Gene Expression Profiles | cell lines with high or low expression of IGLC2 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with IGLC2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing IGLC2 from the GeneSigDB Published Gene Signatures dataset. | |
GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of IGLC2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of IGLC2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of IGLC2 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of IGLC2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
HuBMAP ASCT+B Augmented with RNA-seq Coexpression | cell types associated with IGLC2 gene from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset. | |
HuBMAP Azimuth Cell Type Annotations | cell types associated with IGLC2 gene from the HuBMAP Azimuth Cell Type Annotations dataset. | |
MiRTarBase microRNA Targets | microRNAs targeting IGLC2 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations | gene perturbations changing expression of IGLC2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset. | |
Pathway Commons Protein-Protein Interactions | interacting proteins for IGLC2 from the Pathway Commons Protein-Protein Interactions dataset. | |
Reactome Pathways 2014 | pathways involving IGLC2 protein from the Reactome Pathways dataset. | |
TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with IGLC2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |