IGLC2 Gene

HGNC Family Immunoglobulins (IG)
Name immunoglobulin lambda constant 2 (Kern-Oz- marker)
Description Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025]
Proteins LAC2_HUMAN
NCBI Gene ID 3538
API
Download Associations
Predicted Functions View IGLC2's ARCHS4 Predicted Functions.
Co-expressed Genes View IGLC2's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View IGLC2's ARCHS4 Predicted Functions.

Functional Associations

IGLC2 has 897 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for IGLC2 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CellMarker Gene-Cell Type Associations cell types associated with IGLC2 gene from the CellMarker Gene-Cell Type Associations dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of IGLC2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of IGLC2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing IGLC2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
CTD Gene-Chemical Interactions chemicals interacting with IGLC2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with IGLC2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of IGLC2 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with IGLC2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing IGLC2 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of IGLC2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of IGLC2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
GTEx Tissue-Specific Aging Signatures tissue samples with high or low expression of IGLC2 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of IGLC2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HuBMAP ASCT+B Augmented with RNA-seq Coexpression cell types associated with IGLC2 gene from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.
HuBMAP Azimuth Cell Type Annotations cell types associated with IGLC2 gene from the HuBMAP Azimuth Cell Type Annotations dataset.
MiRTarBase microRNA Targets microRNAs targeting IGLC2 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations gene perturbations changing expression of IGLC2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for IGLC2 from the Pathway Commons Protein-Protein Interactions dataset.
Reactome Pathways 2014 pathways involving IGLC2 protein from the Reactome Pathways dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with IGLC2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.