IGLC2 Gene

HGNC Family	Immunoglobulins (IG)
Name	immunoglobulin lambda constant 2 (Kern-Oz- marker)
Proteins	LAC2_HUMAN
NCBI Gene ID	3538
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

IGLC2 has 879 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.

Click the + buttons to view associations for IGLC2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

IGLC2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of IGLC2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of IGLC2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing IGLC2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with IGLC2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	DISEASES Text-mining Gene-Disease Assocation Evidence Scores	diseases co-occuring with IGLC2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of IGLC2 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with IGLC2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing IGLC2 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of IGLC2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of IGLC2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of IGLC2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of IGLC2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	MiRTarBase microRNA Targets	microRNAs targeting IGLC2 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	gene perturbations changing expression of IGLC2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for IGLC2 from the Pathway Commons Protein-Protein Interactions dataset.
	Reactome Pathways	pathways involving IGLC2 protein from the Reactome Pathways dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with IGLC2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.