ITPR2 Gene

HGNC Family	Ion channels
Name	inositol 1,4,5-trisphosphate receptor, type 2
Description	The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Inositol 1,4,5‐trisphosphate receptor type 2 (ITPR2) is a major endoplasmic reticulum Ca<sup>2+</sup>‐release channel that plays pivotal roles in diverse physiological and pathological processes. Genetic studies have implicated ITPR2 in metabolic regulation—for example, genetic variants at the ITPR2 locus have been associated with altered body fat distribution (see"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "and susceptibility to neurodegeneration, with increased ITPR2 expression observed in patients with amyotrophic lateral sclerosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the exocrine system, ITPR2 (in tandem with IP3R3) has been shown to be essential for proper intracellular Ca<sup>2+</sup> signaling in acinar cells, ensuring effective secretion and nutrient digestion."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Within the cardiovascular system, ITPR2 contributes to pathological Ca<sup>2+</sup> signaling. Although cardiac‐specific deletion of ITPR2 did not significantly affect mitochondrial function in a heart failure model"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ", other studies reveal that aberrant or enhanced ITPR2 expression is linked to maladaptive Ca<sup>2+</sup> handling, hypertrophic gene expression, and diabetic cardiomyopathy through its involvement in mitochondria–endoplasmic reticulum contacts"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "and."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Moreover, in hypertrophic myocardium, increased ITPR2 levels have been associated with pro‐hypertrophic Ca<sup>2+</sup> signals."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the vascular endothelium, ITPR2 mediates Ca<sup>2+</sup> oscillations in response to inflammatory stimuli such as lipopolysaccharide, which in turn activate downstream NFAT signaling and contribute to vascular permeability."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the central nervous system, ITPR2 is predominantly expressed in astrocytes where it orchestrates intracellular Ca<sup>2+</sup> transients that are critical for gliotransmitter release. These Ca<sup>2+</sup> signals regulate synaptic plasticity and play an essential role in developmental synapse elimination"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "and."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Finally, ITPR2 function is further refined by its interaction with proteins that regulate apoptotic Ca<sup>2+</sup> signaling. For instance, in certain cancer cells the sensitivity to pro‐apoptotic Ca<sup>2+</sup> signals has been linked to the expression of ITPR2"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": ", and the Bcl-2 family protein Bok has been shown to bind preferentially to ITPR2—protecting it from proteolysis and thereby influencing cell survival."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these studies highlight ITPR2 as a central mediator of intracellular Ca<sup>2+</sup> dynamics with broad implications for metabolic regulation, cardiovascular function, neuronal plasticity, and disease pathogenesis.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Iris M Heid, Anne U Jackson, Joshua C Randall, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.685"}], "href": "https://doi.org/10.1038/ng.685"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20935629"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20935629"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Michael A van Es, Paul W Van Vught, Hylke M Blauw, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Lancet Neurol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/S1474-4422(07)70222-3"}], "href": "https://doi.org/10.1016/S1474-4422(07"}, {"type": "t", "text": "70222-3) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17827064"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17827064"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Akira Futatsugi, Takeshi Nakamura, Maki K Yamada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1114110"}], "href": "https://doi.org/10.1126/science.1114110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16195467"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16195467"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Gaetano Santulli, Wenjun Xie, Steven R Reiken, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mitochondrial calcium overload is a key determinant in heart failure."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1513047112"}], "href": "https://doi.org/10.1073/pnas.1513047112"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26217001"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26217001"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Shengnan Wu, Qiulun Lu, Qilong Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Binding of FUN14 Domain Containing 1 With Inositol 1,4,5-Trisphosphate Receptor in Mitochondria-Associated Endoplasmic Reticulum Membranes Maintains Mitochondrial Dynamics and Function in Hearts in Vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.117.030235"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.117.030235"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28942427"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28942427"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Shengnan Wu, Qiulun Lu, Ye Ding, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.118.033552"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.118.033552"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30646747"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30646747"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Faye M Drawnel, Dagmar Wachten, Jeffery D Molkentin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.201111095"}], "href": "https://doi.org/10.1083/jcb.201111095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23166348"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23166348"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Rajesh Kumar Gandhirajan, Shu Meng, Harish C Chandramoorthy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI65647"}], "href": "https://doi.org/10.1172/JCI65647"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23348743"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23348743"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Norio Takata, Tsuneko Mishima, Chihiro Hisatsune, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.5289-11.2011"}], "href": "https://doi.org/10.1523/JNEUROSCI.5289-11.2011"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22159127"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22159127"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Junhua Yang, Hongbin Yang, Yali Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.15043"}], "href": "https://doi.org/10.7554/eLife.15043"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27067238"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27067238"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Qian Wang, Ying Kong, Ding-Yu Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-021-23843-0"}], "href": "https://doi.org/10.1038/s41467-021-23843-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34059669"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34059669"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Haidar Akl, Tamara Vervloessem, Santeri Kiviluoto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A dual role for the anti-apoptotic Bcl-2 protein in cancer: mitochondria versus endoplasmic reticulum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2014.04.017"}], "href": "https://doi.org/10.1016/j.bbamcr.2014.04.017"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24768714"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24768714"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Jacqualyn J Schulman, Forrest A Wright, Thomas Kaufmann, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.496570"}], "href": "https://doi.org/10.1074/jbc.M113.496570"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23884412"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23884412"}]}]}]}
Synonyms	ANHD, CFAP48, IP3R2, INSP3R2
Proteins	ITPR2_HUMAN
NCBI Gene ID	3709
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

ITPR2 has 10,797 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 132 datasets.

Click the + buttons to view associations for ITPR2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

ITPR2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ITPR2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of ITPR2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of ITPR2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of ITPR2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ITPR2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of ITPR2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ITPR2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ITPR2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of ITPR2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of ITPR2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with ITPR2 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with ITPR2 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with ITPR2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ITPR2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of ITPR2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of ITPR2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of ITPR2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing ITPR2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing ITPR2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with ITPR2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with ITPR2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing ITPR2 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of ITPR2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with ITPR2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with ITPR2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with ITPR2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with ITPR2 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of ITPR2 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by ITPR2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with ITPR2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with ITPR2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with ITPR2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with ITPR2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with ITPR2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with ITPR2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for ITPR2 protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ITPR2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ITPR2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of ITPR2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing ITPR2 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.