HGNC Family | Keratin associated proteins (KRTAP) |
Name | keratin associated protein 1-4 |
Description | The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al., 2002 [PubMed 12228244]).[supplied by OMIM, Jan 2009] |
Synonyms | KAP1.4, KRTAP1.4 |
Proteins | KRA14_HUMAN |
NCBI Gene ID | 728255 |
API | |
Download Associations | |
Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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KRTAP1-4 has 265 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.
Click the + buttons to view associations for KRTAP1-4 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing KRTAP1-4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
COMPARTMENTS Text-mining Protein Localization Evidence Scores | cellular components co-occuring with KRTAP1-4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. | |
COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of KRTAP1-4 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
COSMIC Cell Line Gene Mutation Profiles | cell lines with KRTAP1-4 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at KRTAP1-4 gene from the ENCODE Histone Modification Site Profiles dataset. | |
ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of KRTAP1-4 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
ENCODE Transcription Factor Targets | transcription factors binding the promoter of KRTAP1-4 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing KRTAP1-4 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with KRTAP1-4 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GO Cellular Component Annotations | cellular components containing KRTAP1-4 protein from the curated GO Cellular Component Annotations dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
InterPro Predicted Protein Domain Annotations | protein domains predicted for KRTAP1-4 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with KRTAP1-4 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |
TRANSFAC Predicted Transcription Factor Targets | transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset. | |