KRTAP1-4 Gene

HGNC Family	Keratin associated proteins (KRTAP)
Name	keratin associated protein 1-4
Description	The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al., 2002 [PubMed 12228244]).[supplied by OMIM, Jan 2009]
Synonyms	KRTAP1.4, KAP1.4
Proteins	KRA14_HUMAN
NCBI Gene ID	728255
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

KRTAP1-4 has 265 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.

Click the + buttons to view associations for KRTAP1-4 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

KRTAP1-4 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing KRTAP1-4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with KRTAP1-4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of KRTAP1-4 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with KRTAP1-4 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at KRTAP1-4 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of KRTAP1-4 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of KRTAP1-4 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing KRTAP1-4 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with KRTAP1-4 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GO Cellular Component Annotations	cellular components containing KRTAP1-4 protein from the curated GO Cellular Component Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of KRTAP1-4 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for KRTAP1-4 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with KRTAP1-4 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of KRTAP1-4 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.