| Name | long intergenic non-protein coding RNA 935 |
| Description | Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and sperm flagellum. Predicted to be active in axonemal A tubule inner sheath. [provided by Alliance of Genome Resources, Mar 2025] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent genome‐wide association studies for word reading ability have implicated noncoding genomic regions in the neurobiology of reading disability and its comorbidity with other neurodevelopmental conditions such as attention deficit/hyperactivity disorder. In particular, one study (1) identified suggestive associations in the region of LINC00935, a long intergenic noncoding RNA. Although the mechanistic details remain to be fully elucidated, current evidence suggests that LINC00935 may contribute to the regulation of gene networks during neurodevelopment, potentially influencing neuronal migration, synaptic formation, or other processes crucial for reading and language acquisition. These findings provide a platform for further functional investigations into how LINC00935 variants might modulate transcriptional regulatory pathways, thereby contributing to individual differences in reading performance and risk for related neurodevelopmental disorders.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Kaitlyn M Price, Karen G Wigg, Yu Feng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Brain Behav (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/gbb.12648"}], "href": "https://doi.org/10.1111/gbb.12648"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32108986"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32108986"}]}]}]}
|
| Synonyms | TEX49 |
| NCBI Gene ID | 255411 |
| API | |
| Download Associations | |
| Predicted Functions |
![]() |
| Co-expressed Genes |
![]() |
| Expression in Tissues and Cell Lines |
![]() |
LINC00935 has 192 functional associations with biological entities spanning 4 categories (chemical, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for LINC00935 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00935 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of LINC00935 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00935 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of LINC00935 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of LINC00935 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of LINC00935 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of LINC00935 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00935 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain LINC00935 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of LINC00935 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of LINC00935 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |