MCTS1 Gene

Name	malignant T cell amplified sequence 1
Description	Enables RNA cap binding activity; ribosomal small subunit binding activity; and translation factor activity, non-nucleic acid binding. Involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Is active in cytoplasm. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Mar 2025]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nMCTS1, also known as the malignant T‐cell amplified sequence 1 oncoprotein, is an evolutionarily conserved regulator of translation that functions in noncanonical translation initiation and reinitiation. Structural and biochemical studies have demonstrated that MCTS1 forms a heterodimer with DENR that binds the small ribosomal subunit, positions the initiator tRNA in the P‐site, and facilitates ribosome recycling on mRNAs that harbor short upstream open reading frames. In addition, detailed promoter and protein‐purification analyses confirm that MCTS1 possesses dedicated RNA binding modules—such as a PUA domain—and a tightly regulated expression program which likely supports its specialized role in translational control."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "7"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn cancer cells, MCTS1 is frequently overexpressed and exerts potent oncogenic effects by promoting cell growth, survival, and genomic instability. Overexpression of this protein has been documented in T‐cell lymphomas and diffuse large B‐cell lymphomas, where it accelerates p53 degradation, deregulates cell cycle checkpoints, and induces centrosome amplification, thereby favoring aneuploidy and chromosomal imbalances. In addition, MCTS1 contributes to the acquisition of stem cell–like traits in solid tumors—including non–small cell lung cancer and laryngeal squamous cell carcinoma—through modulation of key regulators of cell proliferation and cell cycle progression (often involving interactions with proteins such as LARP7 and OTUD6B), and its transcript levels can serve as independent prognostic indicators in head and neck malignancies."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "16"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nNotably, inherited MCTS1 deficiency has recently been associated with an immunological phenotype characterized by diminished translation of critical signaling molecules such as JAK2, impaired interleukin‐23–driven interferon‐γ production, and consequent susceptibility to mycobacterial infections, thereby underscoring a broader physiological significance of MCTS1 in immune regulation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bo Shi, Victor Levenson, Ronald B Gartenhaus "}, {"type": "b", "children": [{"type": "t", "text": "Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.10609"}], "href": "https://doi.org/10.1002/jcb.10609"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12938157"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12938157"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Krystyna Mazan-Mamczarz, Patrick Hagner, Bojie Dai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeted suppression of MCT-1 attenuates the malignant phenotype through a translational mechanism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leuk Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.leukres.2008.08.012"}], "href": "https://doi.org/10.1016/j.leukres.2008.08.012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18824261"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18824261"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Isabel Pérez-Arellano, Roberto Gozalbo-Rovira, Ana Isabel Martínez, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression and purification of recombinant human MCT-1 oncogene in insect cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Protein J (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10930-009-9223-y"}], "href": "https://doi.org/10.1007/s10930-009-9223-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20076993"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20076993"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Ivan B Lomakin, Elena A Stolboushkina, Anand T Vaidya, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2017.06.025"}], "href": "https://doi.org/10.1016/j.celrep.2017.06.025"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28723557"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28723557"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Melanie Weisser, Tanja Schäfer, Marc Leibundgut, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural and Functional Insights into Human Re-initiation Complexes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2017.06.032"}], "href": "https://doi.org/10.1016/j.molcel.2017.06.032"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28732596"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28732596"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Yasar Luqman Ahmed, Sibylle Schleich, Jonathan Bohlen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.2005160"}], "href": "https://doi.org/10.1371/journal.pbio.2005160"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29889857"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29889857"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Ivan B Lomakin, Sergey E Dmitriev, Thomas A Steitz "}, {"type": "b", "children": [{"type": "t", "text": "Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1809688116"}], "href": "https://doi.org/10.1073/pnas.1809688116"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30584092"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30584092"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Bo Shi, Hsin-Ling Hsu, Andy M Evens, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of the candidate MCT-1 oncogene in B- and T-cell lymphoid malignancies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2002-11-3486"}], "href": "https://doi.org/10.1182/blood-2002-11-3486"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12637315"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12637315"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Ravi Kasiappan, Hung-Ju Shih, Kang-Lin Chu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1541-7786.MCR-08-0422"}], "href": "https://doi.org/10.1158/1541-7786.MCR-08-0422"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19372582"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19372582"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Ravi Kasiappan, Hung-Ju Shih, Meng-Hsun Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The antagonism between MCT-1 and p53 affects the tumorigenic outcomes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1476-4598-9-311"}], "href": "https://doi.org/10.1186/1476-4598-9-311"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21138557"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21138557"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Hung-Ju Shih, Kang-Lin Chu, Meng-Hsun Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Cycle (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/cc.11.5.19452"}], "href": "https://doi.org/10.4161/cc.11.5.19452"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22336915"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22336915"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Gaomei Chang, Jiayi Zheng, Wenqin Xiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PKC inhibition of sotrastaurin has antitumor activity in diffuse large B-cell lymphoma via regulating the expression of MCT-1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Biochim Biophys Sin (Shanghai) (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/abbs/gmy021"}], "href": "https://doi.org/10.1093/abbs/gmy021"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29534146"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29534146"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Yonghuai Li, Baolin Wang, Shuyu Gui, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Multiple Copies in T-Cell Malignancy 1 (MCT-1) Promotes the Stemness of Non-Small Cell Lung Cancer Cells via Activating Interleukin-6 (IL-6) Signaling through Suppressing MiR-34a Expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Sci Monit (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.12659/MSM.919690"}], "href": "https://doi.org/10.12659/MSM.919690"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31891569"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31891569"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Jingxian Zhu, Xinmiao Wang, Zhe Shao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic value of malignant T cell-amplified sequence 1 in head and neck squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomark Med (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2217/bmm-2020-0600"}], "href": "https://doi.org/10.2217/bmm-2020-0600"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34704820"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34704820"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Mengsheng Yang, Binjuan Ma, Xiangyi Liu "}, {"type": "b", "children": [{"type": "t", "text": "MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Exp Pharmacol Physiol (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/1440-1681.13640"}], "href": "https://doi.org/10.1111/1440-1681.13640"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35274760"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35274760"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Binjuan Ma, Xiaoquan Wei, Shijie Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2023.08.036"}], "href": "https://doi.org/10.1016/j.bbrc.2023.08.036"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37634410"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37634410"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Jonathan Bohlen, Qinhua Zhou, Quentin Philippot, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cell.2023.09.024"}], "href": "https://doi.org/10.1016/j.cell.2023.09.024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37875108"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37875108"}]}]}]}
Synonyms	MCT-1
Proteins	MCTS1_HUMAN
NCBI Gene ID	28985
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MCTS1 has 5,554 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 113 datasets.

Click the + buttons to view associations for MCTS1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MCTS1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by MCTS1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MCTS1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of MCTS1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of MCTS1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of MCTS1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of MCTS1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MCTS1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of MCTS1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MCTS1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MCTS1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of MCTS1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MCTS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of MCTS1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with MCTS1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with MCTS1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MCTS1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MCTS1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of MCTS1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of MCTS1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing MCTS1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing MCTS1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing MCTS1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with MCTS1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MCTS1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of MCTS1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with MCTS1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with MCTS1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by MCTS1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with MCTS1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MCTS1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MCTS1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MCTS1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MCTS1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MCTS1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MCTS1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MCTS1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of MCTS1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with MCTS1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing MCTS1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of MCTS1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.