MEGF10 Gene

Name	multiple EGF-like-domains 10
Description	This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nMEGF10 is a transmembrane receptor that shares striking structural similarities with the CED-1 protein in Caenorhabditis elegans, thus acting as a conserved mediator in the engulfment of apoptotic cells. In mammalian systems, MEGF10 not only facilitates the clearance of dying cells through a phagocytic pathway but also interacts with regulatory partners such as the ATP binding cassette transporter (ABCA1) and components of the clathrin adaptor complex, thereby modulating cytoskeletal and membrane trafficking events during engulfment."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": " Moreover, MEGF10 contributes to the removal of neurotoxic amyloid‐β peptide via lipid raft–dependent endocytosis, and its role in synapse elimination and axon pruning underscores its importance in maintaining neural circuit integrity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn skeletal muscle, MEGF10 is highly expressed in activated satellite cells where it regulates their proliferation, differentiation, and fusion into mature myofibers. This myogenic role is critical, as evidenced by findings in patients with congenital myopathies—specifically, early onset myopathy with areflexia, respiratory distress, and dysphagia (EMARDD)—in which autosomal recessive mutations in MEGF10 lead to marked muscle weakness and impaired regeneration."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " In addition, transcriptional regulation of MEGF10 by myogenin in muscle cells has been demonstrated, underscoring its role as an essential myogenic regulator; further studies in both patients and animal models have expanded our understanding of how different mutation types contribute to variable phenotypes, ranging from severe neonatal presentations to milder, later-onset forms."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its roles in phagocytosis and myogenesis, MEGF10 is emerging as an important factor in neural development and disease. Expression studies and genetic associations have implicated MEGF10 in neuropsychiatric conditions such as schizophrenia and autism, potentially through its regulation of apoptotic clearance and synaptic remodeling."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}, {"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": " Furthermore, in the context of brain tumors, epigenetic repression of MEGF10 has been observed in glioma and neuroblastoma, where its decreased expression correlates with altered cell migration, proliferation, and apoptosis, thus pointing to a potential tumor-suppressor function."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yannick Hamon, Doriane Trompier, Zhong Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cooperation between engulfment receptors: the case of ABCA1 and MEGF10."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0000120"}], "href": "https://doi.org/10.1371/journal.pone.0000120"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17205124"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17205124"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Emiko Suzuki, Manabu Nakayama "}, {"type": "b", "children": [{"type": "t", "text": "The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2007.03.041"}], "href": "https://doi.org/10.1016/j.yexcr.2007.03.041"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17498693"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17498693"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Emiko Suzuki, Manabu Nakayama "}, {"type": "b", "children": [{"type": "t", "text": "MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2007.06.015"}], "href": "https://doi.org/10.1016/j.yexcr.2007.06.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17643423"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17643423"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Thoudam Debraj Singh, Seung-Yoon Park, Jae-sung Bae, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEGF10 functions as a receptor for the uptake of amyloid-β."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.febslet.2010.08.050"}], "href": "https://doi.org/10.1016/j.febslet.2010.08.050"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20828568"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20828568"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Zhiliu Wu, Jian Qin, Yang You, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-02348-1"}], "href": "https://doi.org/10.1038/s41598-017-02348-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28536440"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28536440"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Clare V Logan, Barbara Lucke, Caroline Pottinger, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.995"}], "href": "https://doi.org/10.1038/ng.995"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22101682"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22101682"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Steven E Boyden, Lane J Mahoney, Genri Kawahara, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurogenetics (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10048-012-0315-z"}], "href": "https://doi.org/10.1007/s10048-012-0315-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22371254"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22371254"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Seung-Yoon Park, Youngeun Yun, Mi-Jin Kim, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Myogenin is a positive regulator of MEGF10 expression in skeletal muscle."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2014.07.061"}], "href": "https://doi.org/10.1016/j.bbrc.2014.07.061"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25044114"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25044114"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Teerin Liewluck, Margherita Milone, Xia Tian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Adult-onset respiratory insufficiency, scoliosis, and distal joint hyperlaxity in patients with multiminicore disease due to novel Megf10 mutations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Muscle Nerve (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mus.25054"}], "href": "https://doi.org/10.1002/mus.25054"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26802438"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26802438"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Mohammad AlMuhaizea, Omar Dabbagh, Hanan AlQudairy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phenotypic Variability of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "MEGF10"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " Variants Causing Congenital Myopathy: Report of Two Unrelated Patients from a Highly Consanguineous Population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes (Basel) (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/genes12111783"}], "href": "https://doi.org/10.3390/genes12111783"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34828389"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34828389"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Y F Lin, X Y Wu, L Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[A family with early onset myopathy caused by MEGF10 gene defect and literature review]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Er Ke Za Zhi (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3760/cma.j.cn112140-20221214-01046"}], "href": "https://doi.org/10.3760/cma.j.cn112140-20221214-01046"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36849355"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36849355"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Xiangning Chen, Xu Wang, Qi Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEGF10 association with schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Psychiatry (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.biopsych.2007.11.003"}], "href": "https://doi.org/10.1016/j.biopsych.2007.11.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18179784"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18179784"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Xiangning Chen, Cuie Sun, Qi Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Apoptotic engulfment pathway and schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0006875"}], "href": "https://doi.org/10.1371/journal.pone.0006875"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19721717"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19721717"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Jessica Charlet, Ayumi Tomari, Anthony R Dallosso, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Carcinog (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mc.22591"}], "href": "https://doi.org/10.1002/mc.22591"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27862318"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27862318"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Guanzhang Li, Zhiliang Wang, Chuanbao Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEGF10, a Glioma Survival-Associated Molecular Signature, Predicts IDH Mutation Status."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dis Markers (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2018/5975216"}], "href": "https://doi.org/10.1155/2018/5975216"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29887919"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29887919"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Hai Yang, Min-Yun Cai, Hua Rong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ZNF667-AS1, a positively regulating MEGF10, inhibits the progression of uveal melanoma by modulating cellular aggressiveness."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biochem Mol Toxicol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jbt.22732"}], "href": "https://doi.org/10.1002/jbt.22732"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33512044"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33512044"}]}]}]}
Synonyms	EMARDD
Proteins	MEG10_HUMAN
NCBI Gene ID	84466
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MEGF10 has 4,971 functional associations with biological entities spanning 9 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 107 datasets.

Click the + buttons to view associations for MEGF10 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MEGF10 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MEGF10 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of MEGF10 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of MEGF10 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of MEGF10 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of MEGF10 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MEGF10 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MEGF10 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MEGF10 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MEGF10 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of MEGF10 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with MEGF10 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MEGF10 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MEGF10 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of MEGF10 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with MEGF10 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with MEGF10 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of MEGF10 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing MEGF10 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing MEGF10 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with MEGF10 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MEGF10 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with MEGF10 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with MEGF10 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with MEGF10 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by MEGF10 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with MEGF10 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MEGF10 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MEGF10 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MEGF10 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MEGF10 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MEGF10 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MEGF10 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MEGF10 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with MEGF10 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with MEGF10 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with MEGF10 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing MEGF10 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of MEGF10 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of MEGF10 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of MEGF10 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.