| HGNC Family | Zinc fingers |
| Name | mex-3 RNA binding family member A |
| Description | Enables RNA binding activity. Located in P-body and cytosol. [provided by Alliance of Genome Resources, Mar 2025] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nMEX3A is a dual‐function RNA‐binding ubiquitin ligase that is frequently overexpressed in a broad spectrum of human malignancies—including lung adenocarcinoma, triple‐negative breast cancer, pancreatic ductal adenocarcinoma, esophageal squamous cell carcinoma, glioma, colorectal, ovarian, endometrial, thyroid, nasopharyngeal cancers, and glioblastoma—with elevated levels correlating with poor prognosis, increased metastasis, and therapeutic resistance."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nMechanistically, MEX3A exerts its oncogenic effects through direct interactions with specific mRNA transcripts and subsequent modulation of their stability or splicing. For example, in lung adenocarcinoma MEX3A binds to and destabilizes LAMA2 mRNA to promote metastasis, while in pancreatic ductal and esophageal cancers, it stabilizes transcripts such as CDK6 to drive cell cycle progression. In ovarian cancer, distinct mechanisms have been reported: one study showed that MEX3A facilitates p53 protein degradation—thereby suppressing ferroptosis—whereas another revealed that MEX3A regulates TIMELESS pre‐mRNA splicing, triggering nonsense‐mediated decay. In glioblastoma, MEX3A targets MSH2 mRNA for deadenylation, compromising DNA mismatch repair and reducing chemosensitivity. Furthermore, MEX3A has been implicated in modulating key oncogenic signaling pathways; its activity has been linked to the activation of PI3K–AKT in lung adenocarcinoma, the RhoA/ROCK1/LIMK1 cascade in breast cancer, NF‑κB signaling via the miR‑3163/SCIN axis in nasopharyngeal carcinoma, and the Wnt/β‑catenin pathway through DVL3 interaction in endometrial carcinoma. Additional regulatory interplay has been observed in thyroid cancer via CREB1, and in colorectal cancer where alterations in glycolytic flux further enhance metastatic traits."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "2", "end_ref": "4"}, {"type": "fg_fs", "start_ref": "8", "end_ref": "14"}, {"type": "fg_f", "ref": "16"}, {"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nCollectively, experimental studies have demonstrated that genetic or pharmacological inhibition of MEX3A markedly impairs cancer cell proliferation, migration, invasion, and in vivo tumor growth, which validates its central role in tumor progression. These findings establish MEX3A not only as a robust prognostic biomarker across multiple cancer types but also as a promising therapeutic target, with its multifaceted regulation of mRNA turnover and signaling pathways underpinning a broad spectrum of oncogenic processes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}, {"type": "fg_fs", "start_ref": "5", "end_ref": "7"}, {"type": "fg_f", "ref": "12"}, {"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Shujun Jiang, Lingjia Meng, Xinye Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A promotes triple negative breast cancer proliferation and migration via the PI3K/AKT signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2020.112191"}], "href": "https://doi.org/10.1016/j.yexcr.2020.112191"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32738346"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32738346"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Jinghui Liang, Haixia Li, Jingyi Han, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-020-02858-3"}], "href": "https://doi.org/10.1038/s41419-020-02858-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32792503"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32792503"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Valentina Panzeri, Isabella Manni, Alessia Capone, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The RNA-binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Oncol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/1878-0261.12847"}], "href": "https://doi.org/10.1002/1878-0261.12847"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33159833"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33159833"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Lei Wei, Bo Wang, Liwen Hu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A is upregulated in esophageal squamous cell carcinoma (ESCC) and promotes development and progression of ESCC through targeting CDK6."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Aging (Albany NY) (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/aging.103196"}], "href": "https://doi.org/10.18632/aging.103196"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33188661"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33188661"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Chao Yang, Haoqiang Zhan, Yiqing Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A contributes to development and progression of glioma through regulating cell proliferation and cell migration and targeting CCL2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-020-03307-x"}], "href": "https://doi.org/10.1038/s41419-020-03307-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33414423"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33414423"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Haixia Li, Jinghui Liang, Jiang Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa-miR-6887-3p."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Commun (Lond) (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cac2.12149"}], "href": "https://doi.org/10.1002/cac2.12149"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33638620"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33638620"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Panpan Zhang, Tong Su, Shu Zhang "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive Analysis of Prognostic Value of MEX3A and Its Relationship with Immune Infiltrates in Ovarian Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2021/5574176"}], "href": "https://doi.org/10.1155/2021/5574176"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34189143"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34189143"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Li Yan, Hongjing Li, Wenbo An, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mex-3 RNA binding MEX3A promotes the proliferation and migration of breast cancer cells via regulating RhoA/ROCK1/LIMK1 signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Bioengineered (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/21655979.2021.1964155"}], "href": "https://doi.org/10.1080/21655979.2021.1964155"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34486491"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34486491"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Xin-Xin Xiang, Yong-Liang Liu, Yi-Fan Kang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A promotes nasopharyngeal carcinoma progression via the miR-3163/SCIN axis by regulating NF-κB signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-022-04871-0"}], "href": "https://doi.org/10.1038/s41419-022-04871-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35490173"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35490173"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Fangfang Li, Chen Zhao, Yuchao Diao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A promotes the malignant progression of ovarian cancer by regulating intron retention in TIMELESS."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-022-05000-7"}], "href": "https://doi.org/10.1038/s41419-022-05000-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35715407"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35715407"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Tian Gan, Yan Wang, Manyi Xie, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-22-2036"}], "href": "https://doi.org/10.1158/0008-5472.CAN-22-2036"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36112059"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36112059"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Cheng-Kai Wang, Tzu-Jou Chen, Grace Y T Tan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A Mediates p53 Degradation to Suppress Ferroptosis and Facilitate Ovarian Cancer Tumorigenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-22-1159"}], "href": "https://doi.org/10.1158/0008-5472.CAN-22-1159"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36354374"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36354374"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Pusheng Yang, Panpan Zhang, Shu Zhang "}, {"type": "b", "children": [{"type": "t", "text": "RNA-Binding Protein MEX3A Interacting with DVL3 Stabilizes Wnt/β-Catenin Signaling in Endometrial Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms24010592"}], "href": "https://doi.org/10.3390/ijms24010592"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36614043"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36614043"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Yong Lu, Tienan Bi, Shenkang Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A promotes angiogenesis in colorectal cancer via glycolysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Libyan J Med (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/19932820.2023.2202446"}], "href": "https://doi.org/10.1080/19932820.2023.2202446"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37155144"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37155144"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Shiji Fang, Liyun Zheng, Xiaoxiao Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A determines in vivo hepatocellular carcinoma progression and induces resistance to sorafenib in a Hippo-dependent way."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hepatol Int (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12072-023-10565-2"}], "href": "https://doi.org/10.1007/s12072-023-10565-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37460832"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37460832"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Guoxun Feng, Penghui Wang, Hongyi Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A induces the development of thyroid cancer via targeting CREB1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Biol Int (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cbin.12076"}], "href": "https://doi.org/10.1002/cbin.12076"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37529875"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37529875"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Jiannan Xu, Songyao Chen, Tengfei Hao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MEX3A promotes colorectal cancer migration, invasion and EMT via regulating the Wnt/β-catenin signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer Res Clin Oncol (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00432-024-05845-9"}], "href": "https://doi.org/10.1007/s00432-024-05845-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38914858"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38914858"}]}]}]}
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| Synonyms | RNF162, MEX-3A, RKHD4 |
| Proteins | MEX3A_HUMAN |
| NCBI Gene ID | 92312 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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MEX3A has 5,179 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 84 datasets.
Click the + buttons to view associations for MEX3A from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of MEX3A gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles | tissues with high or low expression of MEX3A gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of MEX3A gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of MEX3A gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of MEX3A gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of MEX3A gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of MEX3A gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| CCLE Cell Line Proteomics | Cell lines associated with MEX3A protein from the CCLE Cell Line Proteomics dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with MEX3A gene from the CellMarker Gene-Cell Type Associations dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of MEX3A gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of MEX3A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of MEX3A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of MEX3A gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing MEX3A protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with MEX3A protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of MEX3A gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with MEX3A gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| CTD Gene-Disease Associations | diseases associated with MEX3A gene/protein from the curated CTD Gene-Disease Associations dataset. | |
| DeepCoverMOA Drug Mechanisms of Action | small molecule perturbations with high or low expression of MEX3A protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by MEX3A gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Experimental Gene-Disease Association Evidence Scores 2025 | diseases associated with MEX3A gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with MEX3A gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DisGeNET Gene-Disease Associations | diseases associated with MEX3A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. | |
| DisGeNET Gene-Phenotype Associations | phenotypes associated with MEX3A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at MEX3A gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of MEX3A gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of MEX3A gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing MEX3A from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing MEX3A from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of MEX3A gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of MEX3A gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of MEX3A gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of MEX3A gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of MEX3A gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing MEX3A protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Cellular Component Annotations 2023 | cellular components containing MEX3A protein from the curated GO Cellular Component Annotations 2023 dataset. | |
| GO Cellular Component Annotations 2025 | cellular components containing MEX3A protein from the curated GO Cellular Component Annotations 2025 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by MEX3A gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by MEX3A gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of MEX3A gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of MEX3A gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of MEX3A gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of MEX3A gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with MEX3A gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| GWASdb SNP-Disease Associations | diseases associated with MEX3A gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
| GWASdb SNP-Phenotype Associations | phenotypes associated with MEX3A gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
| HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of MEX3A gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Gene Expression Profiles | tissues with high or low expression of MEX3A gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
| HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of MEX3A gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for MEX3A protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of MEX3A gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of MEX3A gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of MEX3A gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Kinase Library Serine Threonine Kinome Atlas | kinases that phosphorylate MEX3A protein from the Kinase Library Serine Threonine Atlas dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of MEX3A gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of MEX3A gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with MEX3A gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of MEX3A gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain MEX3A protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MGI Mouse Phenotype Associations 2023 | phenotypes of transgenic mice caused by MEX3A gene mutations from the MGI Mouse Phenotype Associations 2023 dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of MEX3A gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles | drug perturbations changing expression of MEX3A gene from the NIBR DRUG-seq U2OS MoA Box dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for MEX3A from the Pathway Commons Protein-Protein Interactions dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of MEX3A gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of MEX3A gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PFOCR Pathway Figure Associations 2023 | pathways involving MEX3A protein from the PFOCR Pathway Figure Associations 2023 dataset. | |
| PFOCR Pathway Figure Associations 2024 | pathways involving MEX3A protein from the Wikipathways PFOCR 2024 dataset. | |
| Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of MEX3A gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
| Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of MEX3A gene from the Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures dataset. | |
| Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of MEX3A gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
| Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of MEX3A gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at MEX3A gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of MEX3A gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of MEX3A gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of MEX3A gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Sanger Dependency Map Cancer Cell Line Proteomics | cell lines associated with MEX3A protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset. | |
| Sci-Plex Drug Perturbation Signatures | drug perturbations changing expression of MEX3A gene from the Sci-Plex Drug Perturbation Signatures dataset. | |
| Tabula Sapiens Gene-Cell Associations | cell types with high or low expression of MEX3A gene relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset. | |
| Tahoe Therapeutics Tahoe 100M Perturbation Atlas | drug perturbations changing expression of MEX3A gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. | |
| TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of MEX3A gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of MEX3A gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of MEX3A gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of MEX3A protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with MEX3A protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
