MFSD4B Gene

Name	major facilitator superfamily domain containing 4B
Description	Predicted to enable D-glucose transmembrane transporter activity. Predicted to be involved in hexose transmembrane transport and sodium ion transport. Predicted to be located in apical plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]
NCBI Gene ID	91749
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MFSD4B has 495 functional associations with biological entities spanning 6 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 19 datasets.

Click the + buttons to view associations for MFSD4B from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MFSD4B Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	CellMarker Gene-Cell Type Associations	cell types associated with MFSD4B gene from the CellMarker Gene-Cell Type Associations dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing MFSD4B protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MFSD4B protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with MFSD4B gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MFSD4B gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	GTEx eQTL 2025	SNPs regulating expression of MFSD4B gene from the GTEx eQTL 2025 dataset.
	GTEx Tissue-Specific Aging Signatures	tissue samples with high or low expression of MFSD4B gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
	IMPC Knockout Mouse Phenotypes	phenotypes of mice caused by MFSD4B gene knockout from the IMPC Knockout Mouse Phenotypes dataset.
	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	drug perturbations changing expression of MFSD4B gene from the NIBR DRUG-seq U2OS MoA Box dataset.
	Reactome Pathways 2024	pathways involving MFSD4B protein from the Reactome Pathways 2024 dataset.
	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	gene perturbations changing expression of MFSD4B gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset.
	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	gene perturbations changing expression of MFSD4B gene from the Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures dataset.
	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	gene perturbations changing expression of MFSD4B gene from the Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures dataset.
	RummaGEO Drug Perturbation Signatures	drug perturbations changing expression of MFSD4B gene from the RummaGEO Drug Perturbation Signatures dataset.
	RummaGEO Gene Perturbation Signatures	gene perturbations changing expression of MFSD4B gene from the RummaGEO Gene Perturbation Signatures dataset.
	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	drug perturbations changing expression of MFSD4B gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	tissues with high expression of MFSD4B protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	tissues with high expression of MFSD4B protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	tissues co-occuring with MFSD4B protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.