MRPL23 Gene

HGNC Family	Mitochondrial ribosomal proteins (MRPL, MRPS)
Name	mitochondrial ribosomal protein L23
Description	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe set of studies provided primarily focuses on the mechanisms by which cells control cholesterol homeostasis. In these papers, ATP‐binding cassette transporters—most notably ABCA1 and ABCG1 (and in several cases ABCG4 and related proteins)—are shown to be essential for exporting cellular cholesterol onto extracellular acceptors such as high‐density lipoproteins (HDL). These transporters help prevent cholesterol accumulation, foam cell formation, and the ensuing inflammatory and metabolic disturbances linked with atherosclerosis, lung lipidosis, and even altered immune cell function. For example, several reports demonstrate that up‐regulation of ABCG1 (and ABCA1) by liver X receptor (LXR) or peroxisome proliferator–activated receptor (PPAR) agonists enhances cholesterol efflux from macrophages, endothelial cells, and other tissues, thereby modulating both lipid accumulation and inflammatory responses."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "23"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nImportantly, none of these abstracts address a role for MRPL23. While the collective body of work details key pathways regulating cholesterol efflux, inflammatory signaling, and even impacts on tumor immunity and stem cell mobilization through extracellular lipid transporters, there is no experimental data linking MRPL23 to these processes. MRPL23 is typically recognized as a mitochondrial ribosomal protein involved in mitochondrial protein synthesis, and its function does not overlap with the lipid transport and inflammation‐regulating functions discussed in these studies."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "23"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Taro E Akiyama, Shuichi Sakai, Gilles Lambert, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.22.8.2607-2619.2002"}], "href": "https://doi.org/10.1128/MCB.22.8.2607-2619.2002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11909955"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11909955"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Nan Wang, Debin Lan, Wengen Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0403506101"}], "href": "https://doi.org/10.1073/pnas.0403506101"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15210959"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15210959"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Matthew A Kennedy, Gabriel C Barrera, Kotoka Nakamura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2005.01.002"}], "href": "https://doi.org/10.1016/j.cmet.2005.01.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16054053"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16054053"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Laurent Yvan-Charvet, Tamara Pagler, Emmanuel L Gautier, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1189731"}], "href": "https://doi.org/10.1126/science.1189731"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20488992"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20488992"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Xun Wang, Heidi L Collins, Mollie Ranalletta, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI32057"}], "href": "https://doi.org/10.1172/JCI32057"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17657311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17657311"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Laurent Yvan-Charvet, Mollie Ranalletta, Nan Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI33372"}], "href": "https://doi.org/10.1172/JCI33372"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17992262"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17992262"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Laurent Yvan-Charvet, Carrie Welch, Tamara A Pagler, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.108.793869"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.108.793869"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18852364"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18852364"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Ashley M Vaughan, John F Oram "}, {"type": "b", "children": [{"type": "t", "text": "ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Lipid Res (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1194/jlr.M600218-JLR200"}], "href": "https://doi.org/10.1194/jlr.M600218-JLR200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16902247"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16902247"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Marit Westerterp, Andrew J Murphy, Mi Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCRESAHA.113.301086"}], "href": "https://doi.org/10.1161/CIRCRESAHA.113.301086"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23572498"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23572498"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Fumihiko Matsuura, Nan Wang, Wengen Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI27602"}], "href": "https://doi.org/10.1172/JCI27602"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16670775"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16670775"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Naoki Terasaka, Nan Wang, Laurent Yvan-Charvet, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0704602104"}], "href": "https://doi.org/10.1073/pnas.0704602104"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17846428"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17846428"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Marit Westerterp, Samuel Gourion-Arsiquaud, Andrew J Murphy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Stem Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.stem.2012.04.024"}], "href": "https://doi.org/10.1016/j.stem.2012.04.024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22862945"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22862945"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Naoki Terasaka, Shuiqing Yu, Laurent Yvan-Charvet, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI35470"}], "href": "https://doi.org/10.1172/JCI35470"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18924609"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18924609"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Nan Wang, Mollie Ranalletta, Fumihiko Matsuura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/01.ATV.0000218998.75963.02"}], "href": "https://doi.org/10.1161/01.ATV.0000218998.75963.02"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16556852"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16556852"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Elizabeth J Tarling, Peter A Edwards "}, {"type": "b", "children": [{"type": "t", "text": "ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1113021108"}], "href": "https://doi.org/10.1073/pnas.1113021108"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22095132"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22095132"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Ruud Out, Menno Hoekstra, Kim Habets, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/ATVBAHA.107.156935"}], "href": "https://doi.org/10.1161/ATVBAHA.107.156935"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18006857"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18006857"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Laurent Yvan-Charvet, Tamara A Pagler, Tracie A Seimon, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCRESAHA.110.217281"}], "href": "https://doi.org/10.1161/CIRCRESAHA.110.217281"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20431058"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20431058"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Xiao-Xin Sun, Mu-Shui Dai, Hua Lu "}, {"type": "b", "children": [{"type": "t", "text": "5-fluorouracil activation of p53 involves an MDM2-ribosomal protein interaction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M610621200"}], "href": "https://doi.org/10.1074/jbc.M610621200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17242401"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17242401"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Nan Wang, Laurent Yvan-Charvet, Dieter Lütjohann, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/01.ATV.0000242275.92915.43"}], "href": "https://doi.org/10.1161/01.ATV.0000242275.92915.43"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16917103"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16917103"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Paul T Tarr, Peter A Edwards "}, {"type": "b", "children": [{"type": "t", "text": "ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Lipid Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1194/jlr.M700364-JLR200"}], "href": "https://doi.org/10.1194/jlr.M700364-JLR200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17916878"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17916878"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Kotoka Nakamura, Matthew A Kennedy, Angel Baldán, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M408652200"}], "href": "https://doi.org/10.1074/jbc.M408652200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15319426"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15319426"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Duygu Sag, Caglar Cekic, Runpei Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms7354"}], "href": "https://doi.org/10.1038/ncomms7354"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25724068"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25724068"}]}]}]}
Synonyms	L23MRP, RPL23L
Proteins	RM23_HUMAN
NCBI Gene ID	6150
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MRPL23 has 5,826 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 114 datasets.

Click the + buttons to view associations for MRPL23 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MRPL23 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MRPL23 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of MRPL23 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of MRPL23 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of MRPL23 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MRPL23 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of MRPL23 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MRPL23 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MRPL23 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of MRPL23 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MRPL23 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of MRPL23 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with MRPL23 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with MRPL23 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MRPL23 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MRPL23 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of MRPL23 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of MRPL23 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing MRPL23 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of MRPL23 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing MRPL23 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing MRPL23 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing MRPL23 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing MRPL23 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MRPL23 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing MRPL23 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with MRPL23 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with MRPL23 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with MRPL23 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of MRPL23 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with MRPL23 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with MRPL23 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MRPL23 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MRPL23 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MRPL23 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MRPL23 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MRPL23 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MRPL23 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MRPL23 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with MRPL23 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with MRPL23 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.