HGNC Family | Mitochondrial respiratory chain complexes, ATPases |
Name | ATP synthase F0 subunit 6 |
Synonyms | ATPASE6, MTATP6, ATP6 |
Proteins | ATP6_HUMAN |
NCBI Gene ID | 4508 |
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Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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MT-ATP6 has 930 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 27 datasets.
Click the + buttons to view associations for MT-ATP6 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of MT-ATP6 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
ChEA Transcription Factor Targets | transcription factors binding the promoter of MT-ATP6 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
CORUM Protein Complexes | protein complexs containing MT-ATP6 protein from the CORUM Protein Complexes dataset. | |
CTD Gene-Chemical Interactions | chemicals interacting with MT-ATP6 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
CTD Gene-Disease Associations | diseases associated with MT-ATP6 gene/protein from the curated CTD Gene-Disease Associations dataset. | |
DeepCoverMOA Drug Mechanisms of Action | small molecule perturbations with high or low expression of MT-ATP6 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset. | |
DisGeNET Gene-Disease Associations | diseases associated with MT-ATP6 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. | |
DisGeNET Gene-Phenotype Associations | phenotypes associated with MT-ATP6 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing MT-ATP6 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
GAD Gene-Disease Associations | diseases associated with MT-ATP6 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with MT-ATP6 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of MT-ATP6 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of MT-ATP6 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of MT-ATP6 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of MT-ATP6 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
GO Biological Process Annotations 2015 | biological processes involving MT-ATP6 gene from the curated GO Biological Process Annotations 2015 dataset. | |
GO Cellular Component Annotations 2015 | cellular components containing MT-ATP6 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
GO Molecular Function Annotations 2015 | molecular functions performed by MT-ATP6 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
HuGE Navigator Gene-Phenotype Associations | phenotypes associated with MT-ATP6 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
InterPro Predicted Protein Domain Annotations | protein domains predicted for MT-ATP6 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
KEGG Pathways | pathways involving MT-ATP6 protein from the KEGG Pathways dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of MT-ATP6 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
MiRTarBase microRNA Targets | microRNAs targeting MT-ATP6 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
PFOCR Pathway Figure Associations 2023 | pathways involving MT-ATP6 protein from the PFOCR Pathway Figure Associations 2023 dataset. | |
ProteomicsDB Cell Type and Tissue Protein Expression Profiles | cell types and tissues with high or low expression of MT-ATP6 protein relative to other cell types and tissues from the ProteomicsDB Cell Type and Tissue Protein Expression Profiles dataset. | |
Sanger Dependency Map Cancer Cell Line Proteomics | cell lines associated with MT-ATP6 protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset. | |
WikiPathways Pathways 2014 | pathways involving MT-ATP6 protein from the Wikipathways Pathways 2014 dataset. | |