MT-ND5 Gene

HGNC Family	Mitochondrial respiratory chain complexes
Name	NADH dehydrogenase, subunit 5 (complex I)
Synonyms	MTND5, ND5
Proteins	NU5M_HUMAN
NCBI Gene ID	4540
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MT-ND5 has 697 functional associations with biological entities spanning 6 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 20 datasets.

Click the + buttons to view associations for MT-ND5 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

MT-ND5 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	CORUM Protein Complexes	protein complexs containing MT-ND5 protein from the CORUM Protein Complexes dataset.
	CTD Gene-Disease Associations	diseases associated with MT-ND5 gene/protein from the curated CTD Gene-Disease Associations dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MT-ND5 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with MT-ND5 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with MT-ND5 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of MT-ND5 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of MT-ND5 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GO Biological Process Annotations	biological processes involving MT-ND5 gene from the curated GO Biological Process Annotations dataset.
	GO Cellular Component Annotations	cellular components containing MT-ND5 protein from the curated GO Cellular Component Annotations dataset.
	GO Molecular Function Annotations	molecular functions performed by MT-ND5 gene from the curated GO Molecular Function Annotations dataset.
	HPM Cell Type and Tissue Protein Expression Profiles	cell types and tissues with high or low expression of MT-ND5 protein relative to other cell types and tissues from the HPM Cell Type and Tissue Protein Expression Profiles dataset.
	HPO Gene-Disease Associations	phenotypes associated with MT-ND5 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
	Hub Proteins Protein-Protein Interactions	interacting hub proteins for MT-ND5 from the curated Hub Proteins Protein-Protein Interactions dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with MT-ND5 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for MT-ND5 protein from the InterPro Predicted Protein Domain Annotations dataset.
	KEGG Pathways	pathways involving MT-ND5 protein from the KEGG Pathways dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of MT-ND5 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	MiRTarBase microRNA Targets	microRNAs targeting MT-ND5 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	NURSA Protein Complexes	protein complexs containing MT-ND5 protein recovered by IP-MS from the NURSA Protein Complexes dataset.
	Wikipathways Pathways	pathways involving MT-ND5 protein from the Wikipathways Pathways dataset.